Evidence map›Paper›PMID 22730191›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2012

A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.

Pil Seok Chae, Søren G F Rasmussen, Rohini R Rana, Kamil Gotfryd, Andrew C Kruse, Aashish Manglik, Kyung Ho Cho, Shailika Nurva, Ulrik Gether, Lan Guan and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. HS-AFM Applications to Study Membrane Proteins.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Molecular Structure of the NaInternational journal of molecular sciences · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Specific protonation of acidic residues confers KThe Journal of biological chemistry · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

14 authors.

Pil Seok ChaeDepartment of Bionano Engineering, Hanyang University, Ansan, 426-791, Korea. pchae@hanyang.ac.kr
Søren G F Rasmussen
Rohini R Rana
Kamil Gotfryd
Andrew C Kruse
Aashish Manglik
Kyung Ho Cho
Shailika Nurva
Ulrik Gether
Lan Guan
Claus J Loland
Bernadette Byrne
Brian K Kobilka
Samuel H Gellman

Funding

THE MECHANISM OF BETA2 ADRENOCEPTOR ACTIVATIONR01NS028471 · NINDS · STANFORD UNIVERSITY · PI KOBILKA, BRIAN K · 1990 to 2021
$6.7M
Synthesis/evaluation of novel surfactants for membrane protein structural biologyP01GM075913 · NIGMS · UNIVERSITY OF CHICAGO · PI LAIBLE, PHILIP D · 2005 to 2009
$4.2M
Beta2 Adrenoceptor Structure and Mechanism of ActivationR37NS028471 · NINDS · STANFORD UNIVERSITY · PI KOBILKA, BRIAN K · 2005 to 2011
$3.9M
Novel capture reagents for membrane protein structure determinationR01GM095538 · NIGMS · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GUAN, LAN · 2010 to 2013
$1.2M
Crystallization of eukaryotic facilitated glucose transportersR21HL087895 · NHLBI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GUAN, LAN · 2008 to 2009
$612k
NHLBI NIH HHS R21 HL087895NIGMS NIH HHS P01 GM075913NIGMS NIH HHS P01 GM75913NIGMS NIH HHS R01 GM095538NIGMS NIH HHS R01 GM95538NINDS NIH HHS NS28471NINDS NIH HHS R01 NS028471NINDS NIH HHS R37 NS028471
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hydrophobic and Hydrophilic InteractionsMembrane ProteinsModels, MolecularMolecular StructureSaccharomyces cerevisiaeSolubilityMembrane Proteins

Identifiers

PMID22730191
PMCPMC3493560

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.