Evidence map›Paper›PMID 22729739›Full record

ArticleMolecular and cellular biochemistry2012

Protein expression of ubiquitin in interscapular brown adipose tissue during acclimation of rats to cold: the impact of (∙)NO.

Milica Vucetic, Vesna Otasevic, Ana Stancic, Aleksandra Jankovic, Milica Markelic, Igor Golic, Ksenija Velickovic, Biljana Buzadzic, Aleksandra Korac, Bato Korac

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Article in Molecular and cellular biochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Milica VuceticDepartment of Physiology, Institute for Biological Research Sinisa Stankovic, University of Belgrade, Bulevar despota Stefana 142, 11060 Belgrade, Serbia.
Vesna Otasevic
Ana Stancic
Aleksandra Jankovic
Milica Markelic
Igor Golic
Ksenija Velickovic
Biljana Buzadzic
Aleksandra Korac
Bato Korac
University of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the effects of L-arginine-nitric-oxide ((∙)NO)-producing pathway on protein content of ubiquitin, as an important component of ubiquitin-proteasome system for protein removal, were investigated. We showed that L-arginine markedly decreased ubiquitin protein content in interscapular brown adipose tissue, both in thermogenic inactive (at room temperature) and thermogenic active (on cold) states; while in L-NAME-treated groups this effect was abolished. This result suggests that nitric oxide ((∙)NO), besides well established roles, is involved in this aspect of structure remodeling, as well.

Indexed as

Cold TemperatureAcclimatizationAdipose Tissue, BrownAnimalsEnzyme InhibitorsGene Expression RegulationMaleNG-Nitroarginine Methyl EsterNitric OxideProtein BiosynthesisRatsUbiquitinEnzyme InhibitorsNG-Nitroarginine Methyl EsterNitric OxideUbiquitin

Identifiers

PMID22729739
OpenAlexW2004249047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.