ArticleApplied and environmental microbiology2012
The physiological opportunism of Desulfitobacterium hafniense strain TCE1 towards organohalide respiration with tetrachloroethene.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 31 citations in OpenAlex.
- Structure of a membrane-bound menaquinol:organohalide oxidoreductase.Nature communications · 2023Article
- Proteome adaptations of the organohalide-respiringFrontiers in microbiology · 2023Article
- Stoichiometry of the Gene Products From the Tetrachloroethene Reductive Dehalogenase OperonFrontiers in microbiology · 2022Article
- Tetrachloroethene respiration in Sulfurospirillum species is regulated by a two-component system as unraveled by comparative genomics, transcriptomics, and regulator binding studies.MicrobiologyOpen · 2020Article
- The Membrane-Bound C Subunit of Reductive Dehalogenases: Topology Analysis and Reconstitution of the FMN-Binding Domain of PceC.Frontiers in microbiology · 2018Article
- Isolation and Characterization ofFrontiers in microbiology · 2017Article
- Sister Dehalobacter Genomes Reveal Specialization in Organohalide Respiration and Recent Strain Differentiation Likely Driven by Chlorinated Substrates.Frontiers in microbiology · 2016Article
- Draft genome sequence and characterization of Desulfitobacterium hafniense PCE-S.Standards in genomic sciences · 2015Article
- Functional genotyping of Sulfurospirillum spp. in mixed cultures allowed the identification of a new tetrachloroethene reductive dehalogenase.Applied and environmental microbiology · 2013Article
- Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense.Journal of bacteriology · 2013Article
- Complete genome sequence of Dehalobacter restrictus PER-K23(T.).Standards in genomic sciences · 2013Article
- Evaluation of the inhibitory effects of chloroform on ortho-chlorophenol- and chloroethene-dechlorinating Desulfitobacterium strains.AMB Express · 2013Article
- The restricted metabolism of the obligate organohalide respiring bacterium Dehalobacter restrictus: lessons from tiered functional genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Article
- Impact of vitamin B12 on formation of the tetrachloroethene reductive dehalogenase in Desulfitobacterium hafniense strain Y51.Applied and environmental microbiology · 2012Article
- Ecogenomics of microbial communities in bioremediation of chlorinated contaminated sites.Frontiers in microbiology · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Desulfitobacterium hafniense strain TCE1 is capable of metabolically reducing tetra- and trichloroethenes by organohalide respiration. A previous study revealed that the pce gene cluster responsible for this process is located on an active composite transposon, Tn-Dha1. In the present work, we investigated the effects on the stability of the transposon during successive subcultivations of strain TCE1 in a medium depleted of tetrachloroethene. At the physiological level, an increased fitness of the population was observed after 9 successive transfers and was correlated with a decrease in the level of production of the PceA enzyme. The latter observation was a result of the gradual loss of the pce genes in the population of strain TCE1 and not of a regulation mechanism, as was postulated previously for a similar phenomenon described for Sulfurospirillum multivorans. A detailed molecular analysis of genetic rearrangements occurring around Tn-Dha1 showed two independent but concomitant events, namely, the transposition of the first insertion sequence, ISDha1-a, and homologous recombination across identical copies of ISDha1 flanking the transposon. A new model is proposed for the genetic heterogeneity around Tn-Dha1 in D. hafniense strain TCE1, along with some considerations for the cleavage mechanism mediated by the transposase TnpA1 encoded by ISDha1.
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