Evidence map›Paper›PMID 22729402›Full record

ArticleCurrent infectious disease reports2012

Balamuthia mandrillaris amoebic encephalitis: an emerging parasitic infection.

Francisco G Bravo, Carlos Seas

Abstract read
PubMed Publisher
In one paragraph

Article in Current infectious disease reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
  2. Fatal amoebic meningoencephalitis caused byFrontiers in veterinary science · 2025
    Article
  3. 18F-FDG PET/CT findings in fatalRadiology case reports · 2024
    Article
  4. Article
  5. Article
  6. Mitochondrial genome diversity ofFrontiers in microbiology · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Opportunistic free-living amoebal pathogens.Pathogens and global health · 2022
    Article
  12. Review
  13. Article
  14. Encephalomyelitis Caused byFrontiers in immunology · 2021
    Article
  15. Emerging microbes & infections · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Emerging infections: mimickers of common patterns seen in dermatopathology.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Review
  20. The Epidemiology and Clinical Features of Balamuthia mandrillaris Disease in the United States, 1974-2016.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francisco G BravoInstituto de Medcina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru, fbravopuccio@gmail.com.
Carlos Seas
Universidad Peruana Cayetano Heredia · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balamuthia mandrillaris is a free living amoeba that can be isolated from soil. It is an emerging pathogen causing skin lesions as well as CNS involvement with a fatal outcome if untreated. The infection has been described more commonly in inmunocompetent individuals, mostly males, many children, and with a predilection for population with Hispanic background in cases occurring in the United States. Except for Africa, all continents have reported the disease, although a majority of cases are seen in North and South America. In published reported cases from North America, most patients will debut with neurological symptoms, where as in countries like Peru, a skin lesion will precede other symptoms. The classical skin lesion is a plaque, mostly located on face or knee. Diagnosis requires a high level of suspicion. Therapeutic strategies require a multidrug approach, than includes at least one amebicidal drug, and prolonged periods of treatment.

Identifiers

PMID22729402
OpenAlexW2076365314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.