Evidence map›Paper›PMID 22729219›Full record

ReviewNatural product reports2012

Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.

Heather L Condurso, Steven D Bruner

Abstract readReview
In one paragraph

Review in Natural product reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Bacteria Under Metal Stress-Molecular Mechanisms of Metal Tolerance.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Genome Mining ofMolecules (Basel, Switzerland) · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Refining and expanding nonribosomal peptide synthetase function and mechanism.Journal of industrial microbiology & biotechnology · 2019
    Review
  15. Article
  16. Discovery of the actinoplanic acid pathway inThe Journal of biological chemistry · 2018
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Heather L CondursoDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, USA.
Steven D Bruner

Funding

Mechanisms of nonribosomal peptide natural product biosynthesisR01GM086570 · NIGMS · UNIVERSITY OF FLORIDA · PI BRUNER, STEVEN D · 2009 to 2013
$1.4M
NIGMS NIH HHS GM086570NIGMS NIH HHS R01 GM086570
6 · The paper itself

Abstract

Structural biology has provided significant insights into the complex chemistry and macromolecular organization of nonribosomal peptide synthetases. In addition, novel pathways are continually described, expanding the knowledge of known biosynthetic chemistry.

Indexed as

Biological ProductsMolecular StructurePeptidesPeptide SynthasesProtein ConformationBiological Productsnon-ribosomal peptide synthasePeptidesPeptide Synthases

Identifiers

PMID22729219
PMCPMC3442147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.