Evidence map›Paper›PMID 22728226›Full record

ArticleDrug discovery today2012

The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease.

Bert A 't Hart, David H Abbott, Katsuki Nakamura, Eberhard Fuchs

Open access · greenAbstract read
In one paragraph

Article in Drug discovery today, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 106 citations in OpenAlex.

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  8. Marmosets as models of infectious diseases.Frontiers in cellular and infection microbiology · 2024
    Review
  9. The Development and Validation of Radiopharmaceuticals Targeting Bacterial Infection.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Bert A 't HartDepartment of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands. hart@bprc.nl
David H Abbott
Katsuki Nakamura
Eberhard Fuchs
Biomedical Primate Research Centre · NLGerman Primate Center · DEKyoto University · JPUniversity of Wisconsin–Madison · US

Funding

Role of Androgen Excess in Provoking Oxidative Stress in FemalesP50HD044405 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DUNAIF, ANDREA E · 2002 to 2017
$17.2M
NICHD NIH HHS P50 HD044405
6 · The paper itself

Abstract

The development of biologic molecules (monoclonal antibodies, cytokines, soluble receptors) as specific therapeutics for human disease creates a need for animal models in which safety and efficacy can be tested. Models in lower animal species are precluded when the reagents fail to recognize their targets, which is often the case in rats and mice. In this Feature article we will highlight the common marmoset, a small-bodied nonhuman primate (NHP), as a useful model in biomedical and preclinical translational research.

Indexed as

Disease Models, AnimalAnimalsBiomedical ResearchCallithrixDrug DesignDrug Evaluation, PreclinicalHumansImmunologic FactorsMiceRatsSpecies SpecificityTranslational Research, BiomedicalImmunologic Factors

Identifiers

PMID22728226
PMCPMC6823931
OpenAlexW1974232140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.