ReviewFrontiers in neuroendocrinology2013
Organizational and activational effects of sex steroids on kisspeptin neuron development.
Review in Frontiers in neuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Linking Adult Olfactory Neurogenesis to Social Reproductive Stimuli: Mechanisms and Functions.International journal of molecular sciences · 2024Review
- Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice.Nature communications · 2023Article
- The Behavioral and Neurochemical Changes Induced by Boldenone and/or Tramadol in Adult Male Rats.Neurochemical research · 2023Article
- Medical symptoms and conditions in autistic women.Autism : the international journal of research and practice · 2022Article
- Estrogen Regulation of the Molecular Phenotype and Active Translatome of AVPV Kisspeptin Neurons.Endocrinology · 2021Article
- Alzheimer's pathogenic mechanisms and underlying sex difference.Cellular and molecular life sciences : CMLS · 2021Review
- Sex-dependent effects of chronic variable stress on discrete corticotropin-releasing factor receptor 1 cell populations.Physiology & behavior · 2020Article
- HPG-Dependent Peri-Pubertal Regulation of Adult Neurogenesis in Mice.Frontiers in neuroanatomy · 2020Article
- Delayed Puberty-Phenotypic Diversity, Molecular Genetic Mechanisms, and Recent Discoveries.Endocrine reviews · 2019Review
- Characterization and gonadal hormone regulation of a sexually dimorphic corticotropin-releasing factor receptor 1 cell group.The Journal of comparative neurology · 2019Article
- Metabolic Impact on the Hypothalamic Kisspeptin-Kiss1r Signaling Pathway.Frontiers in endocrinology · 2018Review
- Distribution of corticotropin-releasing factor receptor 1 in the developing mouse forebrain: A novel sex difference revealed in the rostral periventricular hypothalamus.Neuroscience · 2017Article
- Article
- Regulation and Function of RFRP-3 (GnIH) Neurons during Postnatal Development.Frontiers in endocrinology · 2015Review
- Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Impaired GABAB receptor signaling dramatically up-regulates Kiss1 expression selectively in nonhypothalamic brain regions of adult but not prepubertal mice.Endocrinology · 2014Article
- RFamide Peptides in Early Vertebrate Development.Frontiers in endocrinology · 2014Review
- Examination of the influence of leptin and acute metabolic challenge on RFRP-3 neurons of mice in development and adulthood.Neuroendocrinology · 2014Article
- Emerging concepts on the epigenetic and transcriptional regulation of the Kiss1 gene.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2013Review
- Developmental GnRH signaling is not required for sexual differentiation of kisspeptin neurons but is needed for maximal Kiss1 gene expression in adult females.Endocrinology · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Kisspeptin, encoded by the Kiss1 gene, is a neuropeptide required for puberty and adult reproductive function. Understanding the regulation and development of the kisspeptin system provides valuable knowledge about the physiology of puberty and adult fertility, and may provide insights into human pubertal or reproductive disorders. Recent studies, particularly in rodent models, have assessed how kisspeptin neurons develop and how hormonal and non-hormonal factors regulate this developmental process. Exposure to sex steroids (testosterone and estradiol) during critical periods of development can induce organizational (permanent) effects on kisspeptin neuron development, with respect to both sexually dimorphic and non-sexually dimorphic aspects of kisspeptin biology. In addition, sex steroids can also impart activational (temporary) effects on kisspeptin neurons and Kiss1 gene expression at various times during neonatal and peripubertal development, as they do in adulthood. Here, we discuss the current knowledge--and in some cases, lack thereof--of the influence of hormones and other factors on kisspeptin neuronal development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.