ReviewPhysics of life reviews2012
Evolutionary dynamics of RNA-like replicator systems: A bioinformatic approach to the origin of life.
Review in Physics of life reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
59 citing papers in PubMed.
- Exonuclease Ribozyme Encoded in a Circular Genome: On the Initiation of the RNA World.Life (Basel, Switzerland) · 2026Article
- Parasites constrain within-population diversification while accelerating between-population divergence in an RNA replication system.Molecular biology and evolution · 2026Article
- The Emergence of Life in the Light of Evolution.ArXiv · 2026Article
- A symbiotic origin of the ribosome?PNAS nexus · 2026Article
- Thermodynamics of Darwinian selection in molecular replicators.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Generalizing the central dogma as a cross-hierarchical principle of biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- From experimental clues to theoretical modeling: Evolution associated with the membrane-takeover at an early stage of life.PLoS computational biology · 2025Article
- RNA World with Inhibitors.Entropy (Basel, Switzerland) · 2024Article
- Megataxonomy and global ecology of the virosphere.The ISME journal · 2024Review
- Circular at the very beginning: on the initial genomes in the RNA world.RNA biology · 2024Article
- Coevolution of reproducers and replicators at the origin of life and the conditions for the origin of genomes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Towards an RNA/Peptides World by the Direct RNA Template Mechanism: The Emergence of Membrane-Stabilizing Peptides in RNA-Based Protocells.Life (Basel, Switzerland) · 2023Article
- Plausible pathway for a host-parasite molecular replication network to increase its complexity through Darwinian evolution.PLoS computational biology · 2022Article
- RNA World Modeling: A Comparison of Two Complementary Approaches.Entropy (Basel, Switzerland) · 2022Article
- Evolutionary transition from a single RNA replicator to a multiple replicator network.Nature communications · 2022Article
- A Mutation Threshold for Cooperative Takeover.Life (Basel, Switzerland) · 2022Article
- Hitting Times of Some Critical Events in RNA Origins of Life.Life (Basel, Switzerland) · 2021Article
- Nothing in evolution makes sense except in the light of parasitism: evolution of complex replication strategies.Royal Society open science · 2021Article
- The LUCA and its complex virome.Nature reviews. Microbiology · 2020Review
- Global Organization and Proposed Megataxonomy of the Virus World.Microbiology and molecular biology reviews : MMBR · 2020Review
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2 authors.
Funding
Abstract
We review computational studies on prebiotic evolution, focusing on informatic processes in RNA-like replicator systems. In particular, we consider the following processes: the maintenance of information by replicators with and without interactions, the acquisition of information by replicators having a complex genotype-phenotype map, the generation of information by replicators having a complex genotype-phenotype-interaction map, and the storage of information by replicators serving as dedicated templates. Focusing on these informatic aspects, we review studies on quasi-species, error threshold, RNA-folding genotype-phenotype map, hypercycle, multilevel selection (including spatial self-organization, classical group selection, and compartmentalization), and the origin of DNA-like replicators. In conclusion, we pose a future question for theoretical studies on the origin of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.