ArticleBMC pregnancy and childbirth2012
Gaps in the evidence for prevention and treatment of maternal anaemia: a review of systematic reviews.
Article in BMC pregnancy and childbirth, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Mapping the landscape of anaemia research in pregnant and postpartum women: a bibliometric analysis & topic modelling study.Frontiers in global women's health · 2026Pooled it
- Treatment for women with postpartum iron deficiency anaemia.The Cochrane database of systematic reviews · 2024Pooled it
- Treatment for women with postpartum iron deficiency anaemia.The Cochrane database of systematic reviews · 2015Pooled it
- Daily oral iron supplementation during pregnancy.The Cochrane database of systematic reviews · 2015Pooled it
- Integrated care programmes for adults with chronic conditions: a meta-review.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2014Pooled it
- Daily oral iron supplementation during pregnancy.The Cochrane database of systematic reviews · 2012Pooled it
- Could the erythrocyte indices or serum ferritin predict the therapeutic response to a trial with oral iron during pregnancy? Results from the Accuracy study for Maternal Anaemia diagnosis (AMA).BMC pregnancy and childbirth · 2016Trial
- Oral Iron Supplementation in Pregnancy: Current Recommendations and Evidence-Based Medicine.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021Review
- Iron deficiency anaemia in pregnancy: A contemporary review.Obstetric medicine · 2021Review
- The use of intravenous iron in pregnancy: for whom and when? A survey of Australian and New Zealand obstetricians.BMC pregnancy and childbirth · 2020Article
- Screening for iron deficiency and iron deficiency anaemia in pregnancy: a structured review and gap analysis against UK national screening criteria.BMC pregnancy and childbirth · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnaemia, in particular due to iron deficiency, is common in pregnancy with associated negative outcomes for mother and infant. However, there is evidence of significant variation in management. The objectives of this review of systematic reviews were to analyse and summarise the evidence base, identify gaps in the evidence and develop a research agenda for this important component of maternity care.
methodsMultiple databases were searched, including MEDLINE, EMBASE and The Cochrane Library. All systematic reviews relating to interventions to prevent and treat anaemia in the antenatal and postnatal period were eligible. Two reviewers independently assessed data inclusion, extraction and quality of methodology.
results27 reviews were included, all reporting on the prevention and treatment of anaemia in the antenatal (n = 24) and postnatal periods (n = 3). Using AMSTAR as the assessment tool for methodological quality, only 12 of the 27 were rated as high quality reviews. The greatest number of reviews covered antenatal nutritional supplementation for the prevention of anaemia (n = 19). Iron supplementation was the most extensively researched, but with ongoing uncertainty about optimal dose and regimen. Few identified reviews addressed anaemia management post-partum or correlations between laboratory and clinical outcomes, and no reviews reported on clinical symptoms of anaemia.
conclusionsThe review highlights evidence gaps including the management of anaemia in the postnatal period, screening for anaemia, and optimal interventions for treatment. Research priorities include developing standardised approaches to reporting of laboratory outcomes, and information on clinical outcomes relevant to the experiences of pregnant women.
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