ArticleBMC gastroenterology2012
Back-to-back comparison of auto-fluorescence imaging (AFI) versus high resolution white light colonoscopy for adenoma detection.
Article in BMC gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- One in three adenomas could be missed by white-light colonoscopy - findings from a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum.The Cochrane database of systematic reviews · 2016Pooled it
- Image enhanced colonoscopy: updates and prospects-a review.Translational gastroenterology and hepatology · 2023Review
- Mucosal imaging in colon polyps: New advances and what the future may hold.World journal of gastroenterology · 2022Review
- Medical needs related to the endoscopic technology and colonoscopy for colorectal cancer diagnosis.BMC cancer · 2021Article
- Patient-reported outcomes of ductoscopy procedures for pathologic nipple discharge.Breast cancer (Tokyo, Japan) · 2021Article
- Detection of breast cancer precursor lesions by autofluorescence ductoscopy.Breast cancer (Tokyo, Japan) · 2021Observational
- Gastrointestinal diagnosis using non-white light imaging capsule endoscopy.Nature reviews. Gastroenterology & hepatology · 2019Review
- Comparison of the detection of colorectal lesions in different endoscopic modalities: A network meta-analysis and systematic review.Experimental and therapeutic medicine · 2019Article
- Autofluorescence Imaging Reflects the Nuclear Enlargement of Tumor Cells as well as the Cell Proliferation Ability and Aberrant Status of theMolecules (Basel, Switzerland) · 2019Article
- Can technology increase adenoma detection rate?Therapeutic advances in gastroenterology · 2018Review
- The efficacy of autofluorescence imaging in the diagnosis of colorectal diseases.Clinical journal of gastroenterology · 2016Review
- Evaluation of dual-wavelength excitation autofluorescence imaging of colorectal tumours with a high-sensitivity CMOS imager: a cross-sectional study.BMC gastroenterology · 2015Article
- New technologies and techniques to improve adenoma detection in colonoscopy.World journal of gastrointestinal endoscopy · 2015Review
- Detection and miss rates of autofluorescence imaging of adenomatous and polypoid lesions during colonoscopy: a systematic review and meta-analysis.Endoscopy international open · 2015Article
- Endoscopic innovations to increase the adenoma detection rate during colonoscopy.World journal of gastroenterology · 2014Review
- Multiphoton morpho-functional imaging of healthy colon mucosa, adenomatous polyp and adenocarcinoma.Biomedical optics express · 2013Article
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome patients under close colonoscopic surveillance still develop colorectal cancer, thus suggesting the overlook of colorectal adenoma by endoscopists. AFI detects colorectal adenoma as a clear magenta, therefore the efficacy of AFI is expected to improve the detection ability of colorectal adenoma. The aim of this study is to determine the efficacy of AFI in detecting colorectal adenoma.
methodsThis study enrolled 88 patients who underwent colonoscopy at Asahikawa Medical University and Kushiro Medical Association Hospital. A randomly selected colonoscopist first observed the sigmoid colon and rectum with conventional high resolution endosopy (HRE). Then the colonoscopist changed the mode to AFI and handed to the scope to another colonoscopist who knew no information about the HRE. Then the second colonoscopist observed the sigmoid colon and rectum. Each colonoscopist separately recorded the findings. The detection rate, miss rate and procedural time were assessed in prospective manner.
resultsThe detection rate of flat and depressed adenoma, but not elevated adenoma, by AFI is significantly higher than that by HRE. In less-experienced endoscopists, AFI dramatically increased the detection rate (30.3%) and reduced miss rate (0%) of colorectal adenoma in comparison to those of HRE (7.7%, 50.0%), but not for experienced endoscopists. The procedural time of HRE was significantly shorter than that of AFI.
conclusionsAFI increased the detection rate and reduced the miss rate of flat and depressed adenomas. These advantages of AFI were limited to less-experienced endoscopists because experienced endoscopists exhibited a substantially high detection rate for colorectal adenoma with HRE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.