ArticleThe Journal of infectious diseases2012
Entamoeba moshkovskii is associated with diarrhea in infants and causes diarrhea and colitis in mice.
Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Amoebiasis in Iran: a systematic review and meta-analysis.Epidemiology and infection · 2018Pooled it
- A Cross-Sectional Study ofBioMed research international · 2019Trial
- Evaluation of intestinal immune responses to Entamoeba dispar using the first domestic clinical isolate in Japan.PLoS neglected tropical diseases · 2026Article
- Comparative proteomics reveals distinct functions and localization of invasive Entamoeba histolytica and non-invasive Entamoeba moshkovskii proteins.Parasites & vectors · 2026Article
- Extraintestinal Entamoeba moshkovskii Infection, Eastern India.Emerging infectious diseases · 2026Article
- The Taxonomy of the GenusPathogens (Basel, Switzerland) · 2026Review
- Emerging genetic diversity and molecular epidemiology of Entamoeba moshkovskii among patients with acute diarrhoea in Northern India.Tropical medicine and health · 2026Article
- Aspects of Genetic Diversity, Host Specificity and Public Health Significance of Single-Celled Intestinal Parasites Commonly Observed in Humans and Mostly Referred to as 'Non-Pathogenic'.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Review
- Genotypic characterization ofFood and waterborne parasitology · 2025Article
- Spatiotemporal Analysis of the Distribution of Waterborne Diseases in Children Under 5 Years of Age From 2018 to 2022 in the Lemba Health Zone in Kinshasa, DR Congo: A Retrospective and Observational Analysis.Health science reports · 2025Article
- Therapeutic Effect ofMicroorganisms · 2024Article
- Article
- Molecular characterization and zoonotic potential of Entamoeba spp., Enterocytozoon bieneusi and Blastocystis from captive wild animals in northwest China.BMC veterinary research · 2024Article
- Genetic characterization of theParasitology · 2024Article
- Development of nucleic acid lateral flow immunoassay for molecular detection of Entamoeba moshkovskii and Entamoeba dispar in stool samples.Scientific reports · 2024Article
- Prevalence and molecular characterization of Entamoeba moshkovskii in diarrheal patients from Eastern India.PLoS neglected tropical diseases · 2023Article
- Necrotizing amebic colitis in an elder patient: an unexpected autopsy finding.Autopsy & case reports · 2023Article
- Prevalence of Human IntestinalPathogens (Basel, Switzerland) · 2022Review
- Molecular Characterization ofAnimals : an open access journal from MDPI · 2022Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundEntamoeba moshkovskii is prevalent in developing countries and morphologically indistinguishable from pathogenic Entamoeba histolytica and nonpathogenic Entamoeba dispar. It is not known if E. moshkovskii is pathogenic.
methodsMice were intracecally challenged with the trophozoites of each Entamoeba spp. to test the ability to cause diarrhea, and infants in Bangladesh were prospectively observed to see if newly acquired E. moshkovskii infection was associated with diarrhea.
resultsE. moshkovskii and E. histolytica caused diarrhea and weight loss in susceptible mice. E. dispar infected none of the mouse strains tested. In Mirpur, Dhaka, Bangladesh, E. moshkovskii, E. histolytica, and E. dispar were identified in 42 (2.95%), 66 (4.63%), and 5 (0.35%), respectively, of 1426 diarrheal episodes in 385 children followed prospectively from birth to one year of age. Diarrhea occurred temporally with acquisition of a new E. moshkovskii infection: in the 2 months preceding E. moshkvskii-associated diarrhea, 86% (36 of 42) of monthly surveillance stool samples were negative for E. moshkovskii.
conclusionsE. moshkovskii was found to be pathogenic in mice. In children, the acquisition of E. moshkovskii infection was associated with diarrhea. These data are consistent with E. moshkovskii causing disease, indicating that it is important to reexamine its pathogenicity.
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