ReviewProceedings of the National Academy of Sciences of the United States of America2012
Cortical evolution in mammals: the bane and beauty of phenotypic variability.
Review in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 112 citations in OpenAlex.
- Inferring brain-wide interactions using data-constrained recurrent neural network models.Neuron · 2026Article
- Brain activity, disruption and connectivity comparisons identify origins of human metacognition in other primates.Nature human behaviour · 2026Article
- On the impact of tactile processing on motor cortex: how touch shapes motor behaviour.Brain structure & function · 2026Review
- Dual computational systems in the development and evolution of mammalian brains.Science advances · 2026Article
- Reelin Controls the Directional Orientation, Apical Localization and Length of Primary Cilia in Principal Neurons in the Cerebral Cortex.bioRxiv : the preprint server for biology · 2025Article
- Expansion of a conserved architecture drives the evolution of the primate visual cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Development of the rodent prefrontal cortex: circuit formation, plasticity, and impacts of early life stress.Frontiers in neural circuits · 2025Review
- Exploring diversity: a review of animal models for investigating variations in sex characteristics.Frontiers in pediatrics · 2025Review
- Stabilizing selection in an identified multisensory neuron in blind cavefish.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Two common and distinct forms of variation in human functional brain networks.Nature neuroscience · 2024Article
- Homology of neocortical areas in rats and primates based on cortical type analysis: an update of the Hypothesis on the Dual Origin of the Neocortex.Brain structure & function · 2023Article
- Article
- Hemispheric Asymmetries of Individual Differences in Functional Connectivity.Journal of cognitive neuroscience · 2023Article
- Visuomotor interactions in the mouse forebrain mediated by extrastriate cortico-cortical pathways.Frontiers in neuroanatomy · 2023Article
- Cortical field maps across human sensory cortex.Frontiers in computational neuroscience · 2023Review
- Manatee cognition in the wild: an exploration of the manatee mind and behavior through neuroanatomy, psychophysics, and field observations.Animal cognition · 2022Article
- The neuroecology of the water-to-land transition and the evolution of the vertebrate brain.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Evolution of prefrontal cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- The Centriole's Role in Miscarriages.Frontiers in cell and developmental biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Evolution by natural selection, the unifying theory of all biological sciences, provides a basis for understanding how phenotypic variability is generated at all levels of organization from genes to behavior. However, it is important to distinguish what is the target of selection vs. what is transmitted across generations. Physical traits, behaviors, and the extended phenotype are all selected features of an individual, but genes that covary with different aspects of the targets of selection are inherited. Here we review the variability in cortical organization, morphology, and behavior that have been observed across species and describe similar types of variability within species. We examine sources of variability and the constraints that limit the types of changes that evolution has and can produce. Finally, we underscore the importance of how genes and genetic regulatory networks are deployed and interact within an individual, and their relationship to external, physical forces within the environment that shape the ultimate phenotype.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.