ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2012
Neocentromeres and epigenetically inherited features of centromeres.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- Chromosomal rearrangements: tempo and mode of karyotype evolution in Scarabaeoidea.Journal of evolutionary biology · 2026Article
- Characterization of neocentromeric marker chromosome derived from chromosome 11: a rare entity in four patients with acute leukemia.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026Article
- Activation characteristics of Ty3-retrotransposons after spaceflight and genetic stability of insertion sites in rice progeny.Frontiers in plant science · 2024Article
- Review
- Cell cycle control of kinetochore assembly.Nucleus (Austin, Tex.) · 2022Review
- Article
- Molecular Dynamics and Evolution of Centromeres in the Genus Equus.International journal of molecular sciences · 2022Review
- The Cell Biology of Heterochromatin.Cells · 2022Review
- Epigenetic control of centromere: what can we learn from neocentromere?Genes & genomics · 2022Review
- Formation of artificial chromosomes in Caenorhabditis elegans and analyses of their segregation in mitosis, DNA sequence composition and holocentromere organization.Nucleic acids research · 2021Article
- Recent insights into mechanisms preventing ectopic centromere formation.Open biology · 2021Review
- Truly epigenetic: A centromere finds a "neo" home.The Journal of cell biology · 2021Article
- Centromeres under Pressure: Evolutionary Innovation in Conflict with Conserved Function.Genes · 2020Review
- Review
- Polymorphic centromere locations in the pathogenic yeastGenome research · 2020Article
- Centromere deletion ineLife · 2020Article
- Molecular mechanisms of epigenetic inheritance: Possible evolutionary implications.Seminars in cell & developmental biology · 2020Review
- Functional Significance of Satellite DNAs: Insights FromFrontiers in cell and developmental biology · 2020Review
- Article
- Centromere Repeats: Hidden Gems of the Genome.Genes · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Neocentromeres are ectopic sites where new functional kinetochores assemble and permit chromosome segregation. Neocentromeres usually form following genomic alterations that remove or disrupt centromere function. The ability to form neocentromeres is conserved in eukaryotes ranging from fungi to mammals. Neocentromeres that rescue chromosome fragments in cells with gross chromosomal rearrangements are found in several types of human cancers, and in patients with developmental disabilities. In this review, we discuss the importance of neocentromeres to human health and evaluate recently developed model systems to study neocentromere formation, maintenance, and function in chromosome segregation. Additionally, studies of neocentromeres provide insight into native centromeres; analysis of neocentromeres found in human clinical samples and induced in model organisms distinguishes features of centromeres that are dependent on centromere DNA from features that are epigenetically inherited together with the formation of a functional kinetochore.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.