ArticleEvidence-based dentistry2012
10% chlorhexidine varnish did not reduce caries in an adult population.
Article in Evidence-based dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Caries lesion remineralization with fluoride toothpastes and chlorhexidine - effects of application timing and toothpaste surfactant.Journal of applied oral science : revista FOB · 2018Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
designA multi-centre, placebo-controlled, double-blind, randomised clinical trial involving 983 adults (aged 18-80 years old).
interventionThe test group received chlorhexidine diacetate 10% weight per volume (w/v) dental coating and the control group received a placebo coating. Coatings were applied weekly for four weeks and a fifth time six months later. OUTCOME MEASURE: The Pitts and Fyffe taxonomy was used to measure caries progression or reversal, which identifies three stages of lesion on coronal surfaces. The primary outcome was the total net increment in D(1-2)FS; secondary outcomes included the cumulative net D(1-2)FS increment and the total crude D(1-2)FS increment and the cumulative crude D(1-2)FS increment.
resultsNo significant difference was seen between the treatment and placebo groups over a 13 month study period.
conclusionsTen percent chlorhexidine diacetate coating did not show a reduction in caries in an adult population.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.