ArticleBMC infectious diseases2012
Seroprevalence of varicella-zoster virus and predictors for seronegativity in the Amsterdam adult population.
Article in BMC infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Estimation of the burden of varicella in Europe before the introduction of universal childhood immunization.BMC infectious diseases · 2017Pooled it
- Contribution of CNS and extra-CNS infections to neurodegeneration: a narrative review.Journal of neuroinflammation · 2024Review
- Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients.Viruses · 2023Review
- Seropositivity, Risks, and Morbidity From Varicella-Zoster Virus Infections in an Adult PWH Cohort From 2000-2020.Open forum infectious diseases · 2022Article
- Risk factors for some tropical diseases in an African country.BMC public health · 2021Observational
- Epidemiology and factors influencing varicella infections in tropical countries including Sri Lanka.Virusdisease · 2018Review
- Global aspects of viral glycosylation.Glycobiology · 2018Article
- Prevalence of pregnancy-relevant infections in a rural setting of Ghana.BMC pregnancy and childbirth · 2017Article
- Seroprevalence of hepatitis E virus differs in Dutch and first generation migrant populations in Amsterdam, the Netherlands: a cross-sectional study.BMC infectious diseases · 2016Article
- Microbiology laboratory and the management of mother-child varicella-zoster virus infection.World journal of virology · 2016Review
- Varicella-zoster virus susceptibility and primary healthcare consultations in Norway.BMC infectious diseases · 2016Article
- Prevalence of chronic infections and susceptibility to measles and varicella-zoster virus in Latin American immigrants.Infectious diseases of poverty · 2016Article
- Vaccination in elite athletes.Sports medicine (Auckland, N.Z.) · 2014Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the Netherlands, infection with varicella-zoster virus (VZV) is considered a benign common childhood illness and routine vaccination against VZV is not done. In 1995 it was estimated that 98-100% of the adult Dutch general population is immune, yet the estimate is based on a database in which a relative small number of people of non-Dutch ethnic origin were represented. As the city of Amsterdam has large immigrant communities originating from various subtropical and tropical countries, such as Morocco, Surinam, and Turkey with probably lower VZV transmission, this study aimed to estimate the seroprevalence of VZV IgG antibodies (anti-VZV) among various ethnic groups in Amsterdam, and identify factors associated with seronegative VZV status.
methodsThe study was a cross-sectional survey of the Amsterdam population (2004), and the study sample was stratified by age and ethnicity, with deliberate oversampling of minority ethnic groups. Serum samples obtained from 1,341 residents in 2004 were tested for antibodies to VZV. Basic demographic data (gender, age, country of birth, age at immigration and number of children) were also available.
resultsThe anti-VZV seroprevalence in the overall Amsterdam population was estimated to be 94% (95% confidence intervals; 92-96%). Regarding ethnic origin, first generation immigrants (Moroccan immigrants 90%, Surinamese or Antillean immigrants 91%, and Turkish 92%), especially those that migrated after the age of 11 years, were more likely to be anti-VZV seronegative compared to those arriving at an earlier age or those born in the Netherlands (97-98%). Both ethnic origin and generation of immigration were positive predictors for IgG seronegativity to VZV (p<0.015). No other predictors for seronegativity were found.
conclusionThe results of this study imply that about 4-8% of the general adult Amsterdam population is still susceptible to infection with VZV, and that susceptibility is even higher in some immigrant groups. When assessing the risk of infection after VZV exposure alertness is needed for vulnerable persons like pregnant women, patients with hematological malignancies or organ transplants in particular among first-generation immigrants.
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