Evidence map›Paper›PMID 22720681›Full record

ArticleCurrent biology : CB2012

Neurological disorders: towards a mechanistic understanding of restless legs syndrome.

Paul J Shaw, Stephen P Duntley

Abstract readComment
In one paragraph

Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Paul J ShawAnatomy and Neurobiology, Washington University School of Medicine, 660 S. Euclid Ave Campus Box 8108, St. Louis, MO 63110, USA. shawp@pcg.wustl.edu
Stephen P Duntley

Funding

FUNCTIONAL ANALYSIS OF SLEEP HOMEOSTASIS IN DROSOPHILAR01NS051305 · NINDS · WASHINGTON UNIVERSITY · PI SHAW, PAUL J · 2005 to 2023
$6.1M
NINDS NIH HHS R01 NS051305
6 · The paper itself

Abstract

Restless legs syndrome is a curious neurological disorder of unknown aetiology. A new study has found that Drosophila mutants in the fly homologue of a human gene, BTBD9, that has been implicated as a risk factor for restless legs display important features of the syndrome.

Indexed as

AnimalsBrainCarrier ProteinsDopamineDrosophila ProteinsHumansIronRestless Legs SyndromeSleep DeprivationBTBD9 protein, DrosophilaCarrier ProteinsDopamineDrosophila ProteinsIron

Identifiers

PMID22720681
PMCPMC3741047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.