ArticlePloS one2012
Evaluation of 16S rDNA-based community profiling for human microbiome research.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
162 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hawaiian Fungal Amplicon Sequence Variants Reveal Otherwise Hidden Biogeography.Microbial ecology · 2022Pooled it
- Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study.The Lancet. Respiratory medicine · 2014Trial
- The Human Microbiome Project strategy for comprehensive sampling of the human microbiome and why it matters.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2013Trial
- The dental plaque microbiome in health and disease.PloS one · 2013Trial
- The diagnostic potential of combined quantitative polymerase chain reaction and next-generation sequencing using the same primers for periprosthetic joint infection.Microbiology spectrum · 2026Article
- Diversity and Functional Predictions of Gut Microbiota in Vietnamese Children Aged 6-24 Months with Persistent Diarrhea of Unknown Etiology.Pathogens (Basel, Switzerland) · 2025Article
- Bioluminescent monitoring of a co-culture model of pathogen growth to identify a novel probiotic bacterium.BMC research notes · 2025Article
- Integrating the milk microbiome signatures in mastitis: milk-omics and functional implications.World journal of microbiology & biotechnology · 2025Review
- Selection for stress tolerance and longevity in Drosophila melanogaster have strong impacts on microbiome profiles.Scientific reports · 2024Article
- Microbial dark matter sequences verification in amplicon sequencing and environmental metagenomics data.Frontiers in microbiology · 2023Article
- Multiple Sclerosis and Microbiome.Biomolecules · 2022Review
- The effect of mindfulness-based stress reduction on the urinary microbiome in interstitial cystitis.International urogynecology journal · 2022Article
- Dynamics of Microbial Communities in Phototrophic Polyhydroxyalkanoate Accumulating Cultures.Microorganisms · 2022Article
- The impact of cefuroxime prophylaxis on human intestinal microbiota in surgical oncological patients.Frontiers in microbiomes · 2022Article
- Irisin attenuates inflammation in a mouse model of ulcerative colitis by altering the intestinal microbiota.Experimental and therapeutic medicine · 2021Article
- Complex species and strain ecology of the vaginal microbiome from pregnancy to postpartum and association with preterm birth.Med (New York, N.Y.) · 2021Article
- Comparison of different cultures and culturing conditions for the biological deterioration of organic load from real saline bilge wastewater: microbial diversity insights and ecotoxicity assessment.Environmental science and pollution research international · 2021Article
- The azithromycin to prevent wheezing following severe RSV bronchiolitis-II clinical trial: Rationale, study design, methods, and characteristics of study population.Contemporary clinical trials communications · 2021Article
- Probiotics Do Not Alter the Long-Term Stability of the Supragingival Microbiota in Healthy Subjects: A Randomized Controlled Trial.Pathogens (Basel, Switzerland) · 2021Article
- Article
102 more citing papers are in PubMed but not listed here.
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Authors and funding
1 author.
Funding
Abstract
The Human Microbiome Project will establish a reference data set for analysis of the microbiome of healthy adults by surveying multiple body sites from 300 people and generating data from over 12,000 samples. To characterize these samples, the participating sequencing centers evaluated and adopted 16S rDNA community profiling protocols for ABI 3730 and 454 FLX Titanium sequencing. In the course of establishing protocols, we examined the performance and error characteristics of each technology, and the relationship of sequence error to the utility of 16S rDNA regions for classification- and OTU-based analysis of community structure. The data production protocols used for this work are those used by the participating centers to produce 16S rDNA sequence for the Human Microbiome Project. Thus, these results can be informative for interpreting the large body of clinical 16S rDNA data produced for this project.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.