ArticlePLoS computational biology2012
Fast coding of orientation in primary visual cortex.
Article in PLoS computational biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Stimulus-dependent differences in cortical versus subcortical contributions to visual detection in mice.Current biology : CB · 2024Article
- Asymmetries around the visual field: From retina to cortex to behavior.PLoS computational biology · 2022Article
- Sparse Coding in Temporal Association Cortex Improves Complex Sound Discriminability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Frequency-separated principal component analysis of cortical population activity.Journal of neurophysiology · 2020Article
- PV+ Cells Enhance Temporal Population Codes but not Stimulus-Related Timing in Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Emergence of Binocular Disparity Selectivity through Hebbian Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Cracking the Neural Code for Sensory Perception by Combining Statistics, Intervention, and Behavior.Neuron · 2017Review
- A Readout Mechanism for Latency Codes.Frontiers in computational neuroscience · 2016Article
- Neural population coding: combining insights from microscopic and mass signals.Trends in cognitive sciences · 2015Review
- Reading spike timing without a clock: intrinsic decoding of spike trains.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- Strabismus disrupts binocular synaptic integration in primary visual cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Distinct effects of brief and prolonged adaptation on orientation tuning in primary visual cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Perceptual decision making "through the eyes" of a large-scale neural model of v1.Frontiers in psychology · 2013Article
- Precise-spike-driven synaptic plasticity: learning hetero-association of spatiotemporal spike patterns.PloS one · 2013Article
- Neural variability, or lack thereof.Frontiers in computational neuroscience · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Understanding how populations of neurons encode sensory information is a major goal of systems neuroscience. Attempts to answer this question have focused on responses measured over several hundred milliseconds, a duration much longer than that frequently used by animals to make decisions about the environment. How reliably sensory information is encoded on briefer time scales, and how best to extract this information, is unknown. Although it has been proposed that neuronal response latency provides a major cue for fast decisions in the visual system, this hypothesis has not been tested systematically and in a quantitative manner. Here we use a simple 'race to threshold' readout mechanism to quantify the information content of spike time latency of primary visual (V1) cortical cells to stimulus orientation. We find that many V1 cells show pronounced tuning of their spike latency to stimulus orientation and that almost as much information can be extracted from spike latencies as from firing rates measured over much longer durations. To extract this information, stimulus onset must be estimated accurately. We show that the responses of cells with weak tuning of spike latency can provide a reliable onset detector. We find that spike latency information can be pooled from a large neuronal population, provided that the decision threshold is scaled linearly with the population size, yielding a processing time of the order of a few tens of milliseconds. Our results provide a novel mechanism for extracting information from neuronal populations over the very brief time scales in which behavioral judgments must sometimes be made.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.