ArticleJournal of clinical microbiology2012
Differentiation of Streptococcus pneumoniae from nonpneumococcal streptococci of the Streptococcus mitis group by matrix-assisted laser desorption ionization-time of flight mass spectrometry.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Early-life carriage and antibiotic resistance ofFrontiers in microbiology · 2026Article
- Advancing metagenomic classification with NABAS+: a novel alignment-based approach.NAR genomics and bioinformatics · 2025Article
- Review
- A novel LAMP-based assay for the identification ofJournal of clinical microbiology · 2024Article
- Molecular identification and antimicrobial resistance patterns of enterobacterales in community urinary tract infections among indigenous women in Ecuador: addressing microbiological misidentification.BMC infectious diseases · 2024Article
- Development of an automated amplicon-based next-generation sequencing pipeline for rapid detection of bacteria and fungi directly from clinical specimens.Journal of clinical microbiology · 2024Article
- Performance assessment of the Bruker Biotyper MALDI-TOF MS for the identification of difficult-to-identify viridans group streptococci.Journal of clinical microbiology · 2023Article
- ExploringJournal of mass spectrometry and advances in the clinical lab · 2023Article
- Performance of Two Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry (MALDI-TOF MS) Systems for Identification of the Viridans Group Streptococci.Infection and drug resistance · 2023Article
- Microbial Identification in the Clinical Microbiology Laboratory Using MALDI-TOF-MS.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Markers for discriminatingCurrent research in microbial sciences · 2021Article
- Molecular Evidence of a Broad Range of Pathogenic Bacteria inTropical medicine and infectious disease · 2021Article
- Post-BMJ case reports · 2021Article
- Isolation and Identification of Optochin-Resistant Viridans Group Streptococci from the Sputum Samples of Adult Patients in Jakarta, Indonesia.International journal of microbiology · 2021Article
- Identification of Clinically RelevantPathogens (Basel, Switzerland) · 2020Article
- Strategy using a new antigenic test for rapid diagnosis of Streptococcus pneumoniae infection in respiratory samples from children consulting at hospital.BMC microbiology · 2020Article
- Article
- Diverse Streptococcus pneumoniae Strains Drive a Mucosal-Associated Invariant T-Cell Response Through Major Histocompatibility Complex class I-Related Molecule-Dependent and Cytokine-Driven Pathways.The Journal of infectious diseases · 2018Article
- A Case of Recurrent Erysipelas Caused byCase reports in infectious diseases · 2018Article
- Assessment of a novel bile solubility test and MALDI-TOF for the differentiation of Streptococcus pneumoniae from other mitis group streptococci.Scientific reports · 2017Article
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4 authors.
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Abstract
The differentiation of species within the Streptococcus mitis group has posed a problem in the routine diagnostic microbiology laboratory for some time. It also constitutes a major weakness of recently introduced matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) fingerprinting systems. As the phylogenetic resolution of the spectral similarity measures employed by these systems is insufficient to reliably distinguish between the most closely related members of the group, the major pathogen Streptococcus pneumoniae is frequently misidentified. In this study, a comparative analysis of MALDI-TOF spectra of several species from the S. mitis group has been performed in order to identify single peaks that could be used to improve mass spectrometry-based identification of the respective species. A characteristic peak profile could be identified that unambiguously distinguished the 14 S. pneumoniae isolates studied from 33 nonpneumococcal isolates of the S. mitis group. In addition, specific peak combinations could be assigned to other members of the group. The findings of this study suggest that it is possible to distinguish different species of the S. mitis group by close analysis of their mass peak profiles.
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