ArticlePlant physiology2012
Arabidopsis class I and class II TCP transcription factors regulate jasmonic acid metabolism and leaf development antagonistically.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers.
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172 citing papers in PubMed, 337 citations in OpenAlex.
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- Genome-Wide Characterization of TCP Transcription Factors in Common Glasswort (International journal of molecular sciences · 2026Article
- Complex Interplay of Tandem, Segmental, Whole Genome Duplication, and Re-organization Drives Expansion of SAUR Gene Family in Brassicaceae.Biochemical genetics · 2026Article
- Genome-wide characterization of the TCP family in Lagerstroemia and functional analysis of LfiTCP12 uncover its role in shoot branching promotion.Plant cell reports · 2026Article
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- Integrative nuclear and total proteomics of compound leaves in semi-leafless and leafed pea cultivars reveal regulatory cues in leaf development.BMC plant biology · 2026Article
- Genome-wide identification of TCP gene family and gene editing of BjTCP18 genes increases branching in Brassica juncea.Functional & integrative genomics · 2025Article
- Genome-wide identification and expression analysis of thePhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Genome-Wide Identification of thePlants (Basel, Switzerland) · 2025Article
- Evolution and comparison of the expression of TCP genes in the benincaseae and cucurbiteae tribes.Scientific reports · 2025Article
- Genome-wide identification and expression analysis of the3 Biotech · 2025Article
- Systematic Analysis of thePlants (Basel, Switzerland) · 2025Article
- Genome-Wide Exploration and Characterization of theInternational journal of molecular sciences · 2025Article
- Overexpression ofInternational journal of molecular sciences · 2025Article
- Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2025Article
- Transcriptomics and Plant Hormone Analysis Reveal the Mechanism of Branching Angle Formation in Tea Plants (International journal of molecular sciences · 2025Article
- Decoding Plant-Pathogen Interactions: A Comprehensive Exploration of Effector-Plant Transcription Factor Dynamics.Molecular plant pathology · 2025Review
- Unveiling kiwifruit TCP genes: evolution, functions, and expression insights.Plant signaling & behavior · 2024Article
112 more citing papers are in PubMed but not listed here.
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12 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR1 (TCP) transcription factors control developmental processes in plants. The 24 TCP transcription factors encoded in the Arabidopsis (Arabidopsis thaliana) genome are divided into two classes, class I and class II TCPs, which are proposed to act antagonistically. We performed a detailed phenotypic analysis of the class I tcp20 mutant, showing an increase in leaf pavement cell sizes in 10-d-old seedlings. Subsequently, a glucocorticoid receptor induction assay was performed, aiming to identify potential target genes of the TCP20 protein during leaf development. The LIPOXYGENASE2 (LOX2) and class I TCP9 genes were identified as TCP20 targets, and binding of TCP20 to their regulatory sequences could be confirmed by chromatin immunoprecipitation analyses. LOX2 encodes for a jasmonate biosynthesis gene, which is also targeted by class II TCP proteins that are under the control of the microRNA JAGGED AND WAVY (JAW), although in an antagonistic manner. Mutation of TCP9, the second identified TCP20 target, resulted in increased pavement cell sizes during early leaf developmental stages. Analysis of senescence in the single tcp9 and tcp20 mutants and the tcp9tcp20 double mutants showed an earlier onset of this process in comparison with wild-type control plants in the double mutant only. Both the cell size and senescence phenotypes are opposite to the known class II TCP mutant phenotype in JAW plants. Altogether, these results point to an antagonistic function of class I and class II TCP proteins in the control of leaf development via the jasmonate signaling pathway.
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