ReviewWiener medizinische Wochenschrift (1946)2012
HLA class I expression in the human placenta.
Review in Wiener medizinische Wochenschrift (1946), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Genome-edited allogeneic CAR-T cells: the next generation of cancer immunotherapies.Journal of hematology & oncology · 2025Review
- The modeling of human implantation and early placentation: achievements and perspectives.Human reproduction update · 2025Review
- Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts.Nature biomedical engineering · 2024Article
- Cord blood-derived CD19-specific chimeric antigen receptor T cells: an off-the-shelf promising therapeutic option for treatment of diffuse large B-cell lymphoma.Frontiers in immunology · 2023Article
- Advances in the study of HLA class Ib in maternal-fetal immune tolerance.Frontiers in immunology · 2022Review
- Human Tissue-Resident Memory T Cells in the Maternal-Fetal Interface. Lost Soldiers or Special Forces?Cells · 2020Review
- 'Off-the-shelf' allogeneic CAR T cells: development and challenges.Nature reviews. Drug discovery · 2020Review
- Maternal-Fetal Interplay in Zika Virus Infection and Adverse Perinatal Outcomes.Frontiers in immunology · 2020Review
- Relationship between HLA-DPA1 genetic polymorphism and anembryonic pregnancy.Molecular genetics & genomic medicine · 2020Article
- Paving the Way Towards Universal Chimeric Antigen Receptor Therapy in Cancer Treatment: Current Landscape and Progress.Frontiers in immunology · 2020Review
- The microstructure in the placenta is influenced by the functional diversity of HLA-G allelic variants.Immunogenetics · 2019Article
- Evidence for Differential Glycosylation of Trophoblast Cell Types.Molecular & cellular proteomics : MCP · 2016Article
- Functional glycosylation in the human and mammalian uterus.Fertility research and practice · 2015Review
- Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model.Immunogenetics · 2014Article
- Immunotherapy for Lung Cancer: Has it Finally Arrived?Frontiers in oncology · 2014Review
- The role of environmental factors in modulating immune responses in early life.Frontiers in immunology · 2014Review
- Manifestations of immune tolerance in the human female reproductive tract.Frontiers in immunology · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Placental trophoblast cells of the semi-allogenic human conceptus invade deeply into maternal uterine tissue. From a classical immunoiogic point of view this invasion and the following growth and development of the fetus in the uterus have to be tolerated by a pregnant woman's immune system. Among the various possible protective mechanisms that may be involved, the unique expression pattern of HLA class I molecules seems to be relevant. Besides many other differences between placentation and organ transplantation, this extraordinary HLA class I expression on trophoblast explains why pregnancy should not be considered an immunologic paradox but rather a fascinating example of a very special challenge for the female immune system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.