ArticleSurgical endoscopy2012
Impaired postoperative EGJ relaxation as a determinant of post laparoscopic fundoplication dysphagia: a study with high-resolution manometry before and after surgery.
Article in Surgical endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 44 citations in OpenAlex.
- High-Resolution Manometry Improves the Diagnosis of Esophageal Motility Disorders in Patients With Dysphagia: A Randomized Multicenter Study.The American journal of gastroenterology · 2016Trial
- Utilizing Esophageal Motility Tests in Diagnosing and Evaluating Gastroesophageal Reflux Disease.Diagnostics (Basel, Switzerland) · 2024Review
- Manometric identikit of a functioning and effective fundoplication for gastroesophageal reflux disease in the high-resolution manometry ERA.United European gastroenterology journal · 2024Article
- The Impact of Magnetic Sphincter Augmentation (MSA) on Esophagogastric Junction (EGJ) and Esophageal Body Physiology and Manometric Characteristics.Annals of surgery · 2023Article
- Multi-society consensus conference and guideline on the treatment of gastroesophageal reflux disease (GERD).Surgical endoscopy · 2023Article
- More beads, more peristaltic reserve, better outcomes: factors predicting postoperative dysphagia after magnetic sphincter augmentation.Surgical endoscopy · 2021Article
- Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update.Journal of clinical medicine · 2020Review
- Preoperative High-Resolution Manometry Criteria are Associated with Dysphagia After Nissen Fundoplication.World journal of surgery · 2019Article
- The role of preoperative high resolution manometry in predicting dysphagia after laparoscopic Nissen fundoplication.Surgical endoscopy · 2018Article
- High-resolution Manometry in Patients with Gastroesophageal Reflux Disease Before and After Fundoplication.Journal of neurogastroenterology and motility · 2017Article
- Advances in the evaluation and management of esophageal disease of systemic sclerosis.Current rheumatology reports · 2015Review
- Electrical stimulation therapy for gastroesophageal reflux disease.Journal of neurogastroenterology and motility · 2014Article
- Treatment implications of high-resolution manometry findings: options for patients with esophageal dysmotility.Current treatment options in gastroenterology · 2014Article
- Post-fundoplication high-resolution esophageal manometry in a patient with Ehlers-Danlos syndrome.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic fundoplication (FP) reduces gastroesophageal reflux (GER) efficiently. Dysphagia is its main complication, but no clear data have been published in literature to evaluate risk factors associated with it. The goal of this retrospective study was to identify factors associated with dysphagia occurring after FP for GER disease, with high-resolution manometry (HRM) performed before and after surgery.
methodsTwenty patients (11 women; mean age, 49 (range, 19-68 years) underwent HRM before and 2-3 months after laparoscopic Nissen-Rossetti FP. Analysis was performed with esophageal pressure topography according to the Chicago Classification.
resultsBefore FP, ten patients had a manometric hiatal hernia (none after FP). Esophagogastric junction (EGJ) pressures increased after surgery (p < 0.01). Bolus pressurization was present in 2% of all swallows before FP and in 22% after (p = 0.01). Postoperative bolus pressurization percentage was significantly correlated with EGJ relaxation as measured with integrated relaxation pressure (IRP) (r = 0.79, p < 0.01). Eight patients reported dysphagia after FP. The only pre- or post-operative parameter significantly associated with dysphagia was postoperative IRP (5.1 mmHg without vs. 10.3 with dysphagia, p < 0.02).
conclusionsFP establishes an efficient antireflux mechanism by correcting hiatal hernia and increasing EGJ pressures. EGJ relaxation as measured by IRP is significantly altered after surgery, leading to more frequent motility disorders, and bolus pressurization. Postoperative dysphagia was associated with higher values of IRP.
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