ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2013
A sympathetic view of human obesity.
Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 38 citations in OpenAlex.
- Cardiovascular response to acute cold stress in non-obese and obese healthy adults.Ethiopian journal of health sciences · 2015Trial
- The ambulatory arterial stiffness index is not a measure of arterial stiffness in a selected group of children at risk of secondary hypertension.European journal of pediatrics · 2026Article
- Workplace Culture and Biomarkers of Health Risk.International journal of environmental research and public health · 2022Article
- Seasonal decrease in thermogenesis and increase in vasoconstriction explain seasonal response to NJournal of neurochemistry · 2019Article
- Fifty years of microneurography: learning the language of the peripheral sympathetic nervous system in humans.Journal of neurophysiology · 2018Review
- Recruitment strategies in efferent sympathetic nerve activity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2017Review
- Adrenal medullary dysfunction as a feature of obesity.International journal of obesity (2005) · 2017Article
- Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity.Scientific reports · 2016Article
- Metabolic syndrome and the hepatorenal reflex.Surgical neurology international · 2016Review
- Metabolic syndrome and the hepatorenal reflex.Surgical neurology international · 2016Review
- Impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine indexes of cardiac sympathetic innervation.Quantitative imaging in medicine and surgery · 2015Article
- Identification of genes whose expression is altered by obesity throughout the arterial tree.Physiological genomics · 2014Article
- Acute cyclooxygenase inhibition does not alter muscle sympathetic nerve activity or forearm vasodilator responsiveness in lean and obese adults.Physiological reports · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Excess adiposity is associated with increased incidence of cardiovascular disease (CVD). Importantly, CVD mortality associated with obesity is more prevalent in young individuals. Elevated sympathetic nervous system (SNS) activity is present in obesity, even in individuals who are young and otherwise healthy. Baseline SNS overactivity, as well as blunted sympathetically mediated thermogenic response to a meal may play a critical role in the development and progression of CVD which is likely to develop as a result of multiple factors. Recent data indicate that SNS activity to the skeletal muscle is directly related to the degree of renal, endothelial and cardiac dysfunction in young individuals. Targeting the SNS may be an attractive and important avenue for the pharmacological treatment of obesity-related disturbances.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.