ArticleSocial cognitive and affective neuroscience2013
Psychological and neural mechanisms of trait mindfulness in reducing depression vulnerability.
Article in Social cognitive and affective neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Linking Cognitive Reappraisal and Expressive Suppression to Mindfulness: A Three-Level Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Mindfulness meditation regulates anterior insula activity during empathy for social pain.Human brain mapping · 2017Trial
- A small randomized pilot study of a workplace mindfulness-based intervention for surgical intensive care unit personnel: effects on salivary α-amylase levels.Journal of occupational and environmental medicine · 2015Trial
- The Role of Heart Rate Variability in Mindfulness-Based Pain Relief.The journal of painTrial
- The Applicability of Forest Therapy for Socially Isolated Young Adults: Parallel Changes in Psychological Distress and Mindfulness.International journal of environmental research and public health · 2026Article
- Mapping Stress, Anxiety, Depression, and Repetitive Negative Thinking Among Non-Western Undergraduate Students: A Network Analysis.PsyCh journal · 2025Article
- Exploring the Effects of Mindfulness on Adolescent Depression-Findings from a Longitudinal Study.Healthcare (Basel, Switzerland) · 2025Article
- Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Association between trait mindfulness and self-efficacy in sports-disadvantaged college students in China: the chain mediating role of exercise motivation and persistence.Frontiers in psychology · 2025Article
- Relationships Between Applied Mindfulness Practice, Chronic Pain, and Pain-Related Functioning in Veterans.The journal of pain · 2024Article
- Treatment condition as a moderator and change in trait mindfulness as a mediator of a brief mindfulness ecological momentary intervention for generalized anxiety disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Rumination-Focused Cognitive Behavioral Therapy Reduces Rumination and Targeted Cross-network Connectivity in Youth With a History of Depression: Replication in a Preregistered Randomized Clinical Trial.Biological psychiatry global open science · 2024Article
- A chain mediation model reveals the association between mindfulness and depression of college students.Scientific reports · 2023Article
- Mindfulness and negative emotions among Chinese college students: chain mediation effect of rumination and resilience.Frontiers in psychology · 2023Article
- Managing depression with complementary and alternative medicine therapies: a scientometric analysis and visualization of research activities.Frontiers in psychiatry · 2023Article
- An observational study of acupuncture and complementary treatments for major depression: Case series from a preliminary study of proposed collaborative care model.Journal of traditional and complementary medicine · 2022Article
- The Relationship between Acceptance and Sleep-Wake Quality before, during, and after the First Italian COVID-19 Lockdown.Clocks & sleep · 2022Article
- The Importance of Awareness, Acceptance, and Alignment With the Self: A Framework for Understanding Self-Connection.Europe's journal of psychology · 2022Article
- Mindful nonreactivity moderates the relationship between posttraumatic stress disorder and depression.Journal of loss & trauma · 2022Article
- Electrophysiological correlates of mindfulness in patients with major depressive disorder.Frontiers in neuroscience · 2022Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Mindfulness-based interventions are effective for reducing depressive symptoms. However, the psychological and neural mechanisms are unclear. This study examined which facets of trait mindfulness offer protection against negative bias and rumination, which are key risk factors for depression. Nineteen male volunteers completed a 2-day functional magnetic resonance imaging study. One day utilized a stress-induction task and the other day utilized a mindful breathing task. An emotional inhibition task was used to measure neural and behavioral changes related to state negative bias, defined by poorer performance in inhibiting negative relative to neutral stimuli. Associations among trait mindfulness [measured by the Five Facet Mindfulness Questionnaire (FFMQ)], trait rumination, and negative bias were examined. Non-reactivity scores on the FFMQ correlated negatively with rumination and negative bias following the stress induction. Non-reactivity was inversely correlated with insula activation during inhibition to negative stimuli after the mindful breathing task. Our results suggest non-reactivity to inner experience is the key facet of mindfulness that protects individuals from psychological risk for depression. Based on these results, mindfulness could reduce vulnerability to depression in at least two ways: (i) by buffering against trait rumination and negative bias and (ii) by reducing automatic emotional responding via the insula.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.