Evidence map›Paper›PMID 22716995›Full record

ReviewLangmuir : the ACS journal of surfaces and colloids2012

Identifying mechanisms of interfacial dynamics using single-molecule tracking.

Mark Kastantin, Robert Walder, Daniel K Schwartz

Abstract readReview
In one paragraph

Review in Langmuir : the ACS journal of surfaces and colloids, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Diffusion-Controlled Reactions: An Overview.Molecules (Basel, Switzerland) · 2023
    Review
  3. Reversible Adsorption Kinetics of Near Surface Dimer Colloids.Langmuir : the ACS journal of surfaces and colloids · 2016
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Single-molecule resolution of protein structure and interfacial dynamics on biomaterial surfaces.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark KastantinDepartment of Chemical and Biological Engineering, University of Colorado-Boulder, Boulder, Colorado 80309, United States.
Robert Walder
Daniel K Schwartz

Funding

Behavior of biomolecules at controllable solid - water interfacesF32GM091777 · NIGMS · UNIVERSITY OF COLORADO · PI KASTANTIN, MARK JOSEPH · 2010 to 2011
$94k
NIGMS NIH HHS 1F32GM091777-02NIGMS NIH HHS F32 GM091777
6 · The paper itself

Abstract

The "soft" (i.e., noncovalent) interactions between molecules and surfaces are complex and highly varied (e.g., hydrophobic, hydrogen bonding, and ionic), often leading to heterogeneous interfacial behavior. Heterogeneity can arise either from the spatial variation of the surface/interface itself or from molecular configurations (i.e., conformation, orientation, aggregation state, etc.). By observing the adsorption, diffusion, and desorption of individual fluorescent molecules, single-molecule tracking can characterize these types of heterogeneous interfacial behavior in ways that are inaccessible to traditional ensemble-averaged methods. Moreover, the fluorescence intensity or emission wavelength (in resonance energy transfer experiments) can be used to track the molecular configuration and simultaneously directly relate this to the resulting interfacial mobility or affinity. In this feature article, we review recent advances involving the use of single-molecule tracking to characterize heterogeneous molecule-surface interactions including multiple modes of diffusion and desorption associated with both internal and external molecular configuration, Arrhenius-activated interfacial transport, spatially dependent interactions, and many more.

Indexed as

HumansMolecular ConformationOilsProteinsSpectrometry, FluorescenceSurface-Active AgentsWaterOilsProteinsSurface-Active AgentsWater

Identifiers

PMID22716995
PMCPMC3429661

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.