Trial reportInternational wound journal2014
The effectiveness of a four-layer compression bandage system in comparison with Class 3 compression hosiery on healing and quality of life in patients with venous leg ulcers: a randomised controlled trial.
Trial report in International wound journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- Relationships between anxiety, depression and wound healing outcomes in adults: A systematic review and meta-analysis.PloS one · 2025Pooled it
- A meta-review of the impact of compression therapy on venous leg ulcer healing.International wound journal · 2023Pooled it
- Medical compression therapy of the extremities with medical compression stockings (MCS), phlebological compression bandages (PCB), and medical adaptive compression systems (MAC) : S2k guideline of the German Phlebology Society (DGP) in cooperation with the following professional associations: DDG, DGA, DGG, GDL, DGL, BVP.Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Guideline
- Compression bandages or stockings versus no compression for treating venous leg ulcers.The Cochrane database of systematic reviews · 2021Pooled it
- [Medical compression therapy of the extremities with medical compression stockings (MCS), phlebological compression bandages (PCB), and medical adaptive compression systems (MAC) : S2k guideline of the German Phlebology Society (DGP) in cooperation with the following professional associations: DDG, DGA, DGG, GDL, DGL, BVP. German version].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Guideline
- Chronic wounds in Australia: A systematic review of key epidemiological and clinical parameters.International wound journal · 2019Pooled it
- Indications for medical compression stockings in venous and lymphatic disorders: An evidence-based consensus statement.Phlebology · 2018Pooled it
- [Effectiveness of double-layered compression therapy against crepe bandage for healing venous ulcers in primary care. Randomized clinical trial].Atencion primaria · 2020Trial
- Compression therapy in the management of varicose veins.Phlebology · 2024Article
- Black holes in compression therapy: A quest for data.Journal of vascular surgery. Venous and lymphatic disorders · 2024Review
- Daily Duration of Compression Treatment in Chronic Venous Disease Patients: A Systematic Review.Journal of personalized medicine · 2023Review
- The effectiveness of two different sub-bandage pressure values on healing and quality of life outcomes for patients with venous leg ulcers.Postepy dermatologii i alergologii · 2023Article
- Impact of Educational Nursing Intervention on Compression Therapy Adherence and Recurrence of Venous Leg Ulcers: A Quasi-Experimental Study.Ocular oncology and pathology · 2022Article
- Allogeneic ABCB5JID innovations : skin science from molecules to population health · 2022Article
- Predicting delayed healing: The diagnostic accuracy of a venous leg ulcer risk assessment tool.International wound journal · 2018Article
- Evidence-Based Clinical Practice Points for the Management of Venous Ulcers.The Indian journal of surgery · 2018Review
- Venous leg ulcers.BMJ clinical evidence · 2016Review
- Compression for Primary Prevention, Treatment, and Prevention of Recurrence of Venous Leg Ulcers: An Evidence-and Consensus-Based Algorithm for Care Across the Continuum.Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing number of compression systems available for treatment of venous leg ulcers and limited evidence on the relative effectiveness of these systems are available. The purpose of this study was to conduct a randomised controlled trial to compare the effectiveness of a four-layer compression bandage system and Class 3 compression hosiery on healing and quality of life (QL) in patients with venous leg ulcers. Data were collected from 103 participants on demographics, health, ulcer status, treatments, pain, depression and QL for 24 weeks. After 24 weeks, 86% of the four-layer bandage group and 77% of the hosiery group were healed (P = 0·24). Median time to healing for the bandage group was 10 weeks, in comparison with 14 weeks for the hosiery group (P = 0·018). The Cox proportional hazards regression found participants in the four-layer system were 2·1 times (95% CI 1·2-3·5) more likely to heal than those in hosiery, while longer ulcer duration, larger ulcer area and higher depression scores significantly delayed healing. No differences between groups were found in QL or pain measures. Findings indicate that these systems were equally effective in healing patients by 24 weeks; however, a four-layer system may produce a more rapid response.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.