Basic science of cardiac resynchronization therapy: molecular and electrophysiological mechanisms.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Understanding the Mortality Trends in Patients With Ventricular Arrhythmias and Cardiomyopathy: A 25-Year Retrospective Analysis From 1999-2024.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
   Observational
2. Differential effects of semaglutide and colchicine on atrial remodeling in rats with reduced ejection fraction after myocardial infarction.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
   Article
3. Is Resynchronization Pacing Proarrhythmic Among Congenital Heart Patients? An Evaluation and Review.Journal of cardiovascular development and disease · 2026
   Article
4. Metabolic flexibility and reverse remodelling of the failing human heart.European heart journal · 2025
   Article
5. Multipoint Left Ventricular Pacing as Alternative Approach in Cases of Biventricular Pacing Failure.Journal of clinical medicine · 2025
   Review
6. Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential.Nature reviews. Cardiology · 2023
   Review
7. Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue.Journal of molecular and cellular cardiology · 2022
   Article
8. The Evolving Role of Electrocardiography in Cardiac Resynchronization Therapy.Current treatment options in cardiovascular medicine · 2019
   Review
9. Cardiac Resynchronisation Therapy and Cellular Bioenergetics: Effects Beyond Chamber Mechanics.European cardiology · 2019
   Review
10. Prominent differences in left ventricular performance and myocardial properties between right ventricular and left ventricular-based pacing modes in rats.Scientific reports · 2017
    Article
11. Autonomic Modulation in Patients with Heart Failure Increases Beat-to-Beat Variability of Ventricular Action Potential Duration.Frontiers in physiology · 2017
    Article
12. Cardiac dyssynchrony and response to cardiac resynchronisation therapy in heart failure: can genetic predisposition play a role?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2016
    Article
13. Cardiac resynchronization therapy induces adaptive metabolic transitions in the metabolomic profile of heart failure.Journal of cardiac failure · 2015
    Article
14. Optical mapping of optogenetically shaped cardiac action potentials.Scientific reports · 2014
    Article
15. Speckle-tracking echocardiography elucidates the effect of pacing site on left ventricular synchronization in the normal and infarcted rat myocardium.PloS one · 2014
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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