ReviewSwiss medical weekly2012
Contrast-induced nephropathy in invasive cardiology.
Review in Swiss medical weekly, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04375787 (High Dose Atorvastatin Raises Threshold of Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
High Dose Atorvastatin Raises Threshold of Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention
Open the trial in the graphWho cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Nicorandil for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: a meta-analysis.Future cardiology · 2025Pooled it
- Evaluating biomarkers for contrast-induced nephropathy following coronary interventions: an umbrella review on meta-analyses.European journal of medical research · 2024Pooled it
- Impact of renal dysfunction on immediate versus staged revascularization of non-culprit lesions in patients with ST segment elevation myocardial infarction: a pre-specified subgroup analysis of the randomized MULTISTARS AMI trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Trial
- Contrast dose reduction with shortened injection durations in coronary CT angiography on 16-cm Wide-detector CT scanner.The British journal of radiology · 2018Trial
- Temporal Dynamics of the Association Between Acute Kidney Injury and Mortality After Transcatheter Aortic Valve Implantation: Insights from Time-Varying and Landmark Survival Analyses.Journal of cardiovascular development and disease · 2025Article
- Expanding Applications of Three-Dimensional Cardiac Mapping Systems: A Review.Journal of clinical medicine · 2025Review
- The impact of preprocedural pulmonary artery systolic pressure on acute kidney injury related to transcatheter aortic valve replacement.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025Article
- Prediction of post-contrast acute kidney injury by bedside ultrasonography.BMC emergency medicine · 2025Observational
- Zero-Contrast Transcatheter Aortic Valve Implantation vs. Standard Practice: Periprocedural and Long-Term Clinical Outcomes.Journal of clinical medicine · 2024Article
- Anisodamine for the prevention of contrast-induced nephropathy in patients with acute coronary syndrome: a pilot systematic review and meta-analysis of randomized controlled trials.Annals of medicine and surgery (2012) · 2024Review
- Evaluating the Image Quality of Neck Structures Scanned on Chest CT with Low-Concentration-Iodine Contrast Media.Tomography (Ann Arbor, Mich.) · 2022Article
- Comparing Trimetazidine with Allopurinol in Prevention of Contrast Induced Nephropathy After Coronary Angiography.Journal of the Saudi Heart Association · 2020Article
- Article
- Evaluation of contrast nephropathy in percutaneous treatment of chronic total occlusions.Interventional medicine & applied science · 2019Article
- The predictive value of the renal resistive index for contrast-induced nephropathy in patients with acute coronary syndrome.BMC cardiovascular disorders · 2019Article
- A New and Simple Risk Predictor of Contrast-Induced Nephropathy in Patients Undergoing Primary Percutaneous Coronary Intervention: TIMI Risk Index.Cardiology research and practice · 2018Article
- miR‑21 attenuates contrast‑induced renal cell apoptosis by targeting PDCD4.Molecular medicine reports · 2017Article
- Expression of neutrophil gelatinase-associated lipocalin in low osmolar contrast-induced nephropathy in rats and the effect of N-acetylcysteine.Experimental and therapeutic medicine · 2016Article
- Neutrophil Gelatinase-Associated Lipocalin as an Early Marker of Contrast-Induced Nephropathy After Elective Invasive Cardiac Procedures.Clinical cardiology · 2016Article
- Acute Kidney Injury: Definition, Pathophysiology and Clinical Phenotypes.The Clinical biochemist. Reviews · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contrast-induced nephropathy (CIN) is an acute renal injury due to the renal toxicity of iodinated contrast media. It is classically defined as a relative (≥25%) or absolute (≥0.5 mg/dl; 44 μmol/l) increase in serum creatinine from baseline value. CIN accounts for 10 to 15% of hospital-acquired acute renal failure and may rarely lead to irreversible renal function loss. Following percutaneous coronary intervention, reported incidence of CIN varies between 0 to more than 20%, depending on the prevalence of risk factors and used definition. Nowadays, the diagnosis of CIN relays on serum creatinine monitoring, although it is a late marker of acute kidney injury. Given the expanding number of percutaneous coronary interventions made in outpatient settings and the morbidity and mortality associated with CIN, early detection of CIN is of utmost clinical relevance. Several plasmatic and urinary biomarkers have been studied in that view, with plasmatic cystatine-C and urinary NGAL being the most promising. As no treatment specifically targets CIN once it develops, the main goal for clinicians remains prevention, with hydration status optimisation being the only proven strategy to date. Here, we will review the recent evidence concerning CIN, its incidence, proposed early diagnostic biomarkers, as well as its treatment and prognostic implication.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.