ArticleOptics express2012
Radioluminescent nanophosphors enable multiplexed small-animal imaging.
Article in Optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025Review
- Combining X-ray excited optical luminescence and X-ray absorption spectroscopy for correlative imaging on the nanoscale.Journal of synchrotron radiation · 2021Article
- High-Z Metal-Organic Frameworks for X-ray Radiation-Based Cancer Theranostics.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Tb-Doped core-shell-shell nanophosphors for enhanced X-ray induced luminescence and sensitization of radiodynamic therapy.Biomaterials science · 2021Article
- Nanoparticles for Cerenkov and Radioluminescent Light Enhancement for Imaging and Radiotherapy.Nanomaterials (Basel, Switzerland) · 2020Review
- Synthesis of Radioluminescent CaFNanomaterials (Basel, Switzerland) · 2020Article
- Radionuclide-Activated Nanomaterials and Their Biomedical Applications.Angewandte Chemie (International ed. in English) · 2019Review
- Green Emitting Cerium Doped CaS Whiskers Grown by Solid State Diffusion Method.Journal of fluorescence · 2018Article
- Gamma rays excited radioluminescence tomographic imaging.Biomedical engineering online · 2018Article
- Bright X-ray and up-conversion nanophosphors annealed using encapsulated sintering agents for bioimaging applications.Journal of materials chemistry. B · 2017Article
- Cone Beam X-ray Luminescence Computed Tomography Based on Bayesian Method.IEEE transactions on medical imaging · 2017Article
- IntrinsicallyAmerican journal of translational research · 2016Article
- In vivo nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging.Nature communications · 2015Article
- Feasibility study of novel endoscopic Cerenkov luminescence imaging system in detecting and quantifying gastrointestinal disease: first human results.European radiology · 2015Article
- Performance evaluation of endoscopic Cerenkov luminescence imaging system: in vitro and pseudotumor studies.Biomedical optics express · 2014Article
- Fluorescent imaging of cancerous tissues for targeted surgery.Advanced drug delivery reviews · 2014Review
- Multifunctional yolk-in-shell nanoparticles for pH-triggered drug release and imaging.Small (Weinheim an der Bergstrasse, Germany) · 2014Article
- Monitoring pH-triggered drug release from radioluminescent nanocapsules with X-ray excited optical luminescence.ACS nano · 2013Article
- Enhancement of Cerenkov luminescence imaging by dual excitation of Er(3+),Yb(3+)-doped rare-earth microparticles.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We demonstrate the ability to image multiple nanoparticle-based contrast agents simultaneously using a nanophosphor platform excited by either radiopharmaceutical or X-ray irradiation. These radioluminescent nanoparticles emit optical light at unique wavelengths depending on their lanthanide dopant, enabling multiplexed imaging. This study demonstrates the separation of two distinct nanophosphor contrast agents in gelatin phantoms with a recovered phosphor separation correlation of -0.98. The ability to distinguish the two nanophosphors and a Cerenkov component is then demonstrated in a small animal phantom. Combined with the high-resolution potential of low-scattering X-ray excitation, this imaging technique may be a promising method to probe molecular processes in living organisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.