ArticleSkeletal radiology2013
Prediction of hip osteoporotic fractures from composite indices of femoral neck strength.
Article in Skeletal radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Hip structural parameters over 96 weeks in HIV-infected adults switching treatment to tenofovir-emtricitabine or abacavir-lamivudine.PloS one · 2014Trial
- C-reactive protein, bone strength, and nine-year fracture risk: data from the Study of Women's Health Across the Nation (SWAN).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2013Trial
- Association between composite indices of femoral neck strength and odds of hip fracture.Archives of osteoporosis · 2024Article
- Hip Axis Length and Femoral Neck-Shaft Angle as Risk Factors for Proximal Femur Fractures in Octogenarians to Centenarians.Journal of clinical medicine · 2024Article
- Fracture risk prediction in old Chinese people-a narrative review.Archives of osteoporosis · 2023Review
- Hip Fracture Discrimination Based on Statistical Multi-parametric Modeling (SMPM).Annals of biomedical engineering · 2019Article
- Tea Consumption Is Associated with Increased Bone Strength in Middle-Aged and Elderly Chinese Women.The journal of nutrition, health & aging · 2018Article
- Short- and midterm reproducibility of marrow fat measurements using mDixon imaging in healthy postmenopausal women.Skeletal radiology · 2016Article
- Contributions of fat mass and fat distribution to hip bone strength in healthy postmenopausal Chinese women.Journal of bone and mineral metabolism · 2015Article
- Are we taking full advantage of the growing number of pharmacological treatment options for osteoporosis?Current opinion in pharmacology · 2014Review
- Physical activity as determinant of femoral neck strength relative to load in adult women: findings from the hip strength across the menopause transition study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- Article
- Trajectories of femoral neck strength in relation to the final menstrual period in a multi-ethnic cohort.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Article
- The temporal characterization of marrow lipids and adipocytes in a rabbit model of glucocorticoid-induced osteoporosis.Skeletal radiology · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo clarify whether composite hip strength indices improve predictive ability for hip osteoporotic fractures independent of conventional bone mineral density (BMD). SUBJECTS AND
methodsThree hundred and eighty-two health controls and 43 women with hip fractures (aged 28.2-87.7 years, mean age 59.5 ± 9.2 years) were measured by dual energy X-ray absorptiometry for femoral neck bone mineral density (FN_BMD) and proximal femur geometry parameters of hip, and composite hip strength indices (Compression strength index, Bending strength index, and Impact strength index). The association between the studied parameters and the fractures was modelled using multiple logistic regression, including age, height, weight, and menopausal status. Fracture-predicted probability was calculated for each predictor tested. ROC curve areas (AUCs) were calculated for the fracture status, having the calculated fracture-predicted probability as a test variable. AUCs were compared by the Hanley-McNeil test.
resultsWomen with hip fractures had lower FN_BMD, composite hip strength indices, and longer hip axis length than controls, and no significant difference in femoral neck width. Logistic regression showed composite hip strength indices could predict hip fractures risk. To the same extent as FN BMD, Compression Strength Index (CSI) best predicted the risk for each fracture (AUC = 0.787 ± 0.028). When CSI was added to FN_BMD, there was a small but not statistically significant increase in AUC to 0.796 ± 0.027 (P = 0.9018).
conclusionComposite indices of femoral neck strength may be valuable in the assessment of the biomechanics of bone fragility; however, they do not appear to add diagnostic value to the simple measurement of BMD.
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