Evidence map›Paper›PMID 22714020›Full record

ReviewNature reviews. Neuroscience2012

The cognitive neuroscience of ageing.

Cheryl Grady

Registry-linked trialAbstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05929872 (The Efficacy of Strategic Memory Training Coupled With Non-invasive Brain Stimulation Techniques in Healthy Aging Population and Subjective Cognitive Decline Patients), which is not on this map. Cited by 623 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
623citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05929872 nanot yet recruitingnot on this mapstarted 2023, after this paper: background citation

The Efficacy of Strategic Memory Training Coupled With Non-invasive Brain Stimulation Techniques in Healthy Aging Population and Subjective Cognitive Decline Patients: a Randomized-controlled Study

TypeinterventionalSponsorIRCCS National Neurological Institute "C. Mondino" FoundationRan2023 to 2026Enrolled56ConditionsCognitive Decline, Healthy AgingArmsNon-invasive brain stimulation, Sham non-invasive brain stimulation
3 · Its place in the literature

Who cites it

623 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of transcranial alternating current stimulation on cognitive function in older adults: a systematic review and meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  16. Brain Network Dynamics of Local and Global Predictive Processing in Aging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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563 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Cheryl GradyThe Rotman Research Institute at Baycrest, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada. cgrady@rotman-baycrest.on.ca

Funding

CIHR 14036-4
6 · The paper itself

Abstract

The availability of neuroimaging technology has spurred a marked increase in the human cognitive neuroscience literature, including the study of cognitive ageing. Although there is a growing consensus that the ageing brain retains considerable plasticity of function, currently measured primarily by means of functional MRI, it is less clear how age differences in brain activity relate to cognitive performance. The field is also hampered by the complexity of the ageing process itself and the large number of factors that are influenced by age. In this Review, current trends and unresolved issues in the cognitive neuroscience of ageing are discussed.

Indexed as

AgingNeurosciencesBrainCognitionHumansMale

Identifiers

PMID22714020
PMCPMC3800175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.