Evidence map›Paper›PMID 22713694›Full record

ArticleBMC public health2012

Simulating school closure policies for cost effective pandemic decision making.

Ozgur M Araz, Paul Damien, David A Paltiel, Sean Burke, Bryce van de Geijn, Alison Galvani, Lauren Ancel Meyers

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  11. Costs and benefits of interventions aimed at major infectious disease threats: lessons from the literature.The European journal of health economics : HEPAC : health economics in prevention and care · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ozgur M ArazCollege of Public Health, University of Nebraska Medical Center, Omaha, NE 68198, USA. ozgur.araz@unmc.edu
Paul Damien
David A Paltiel
Sean Burke
Bryce van de Geijn
Alison Galvani
Lauren Ancel Meyers
The University of Texas at Austin · USConnecticut Department of Public Health · USNebraska Medical Center · USYale University · US

Funding

Impacts of Individual and Social Behavior on Influenza Dynamics and ControlU01GM087719 · NIGMS · YALE UNIVERSITY · PI GALVANI, ALISON P, MEYERS, LAUREN ANCEL · 2009 to 2018
$6.3M
6 · The paper itself

Abstract

backgroundAround the globe, school closures were used sporadically to mitigate the 2009 H1N1 influenza pandemic. However, such closures can detrimentally impact economic and social life.

methodsHere, we couple a decision analytic approach with a mathematical model of influenza transmission to estimate the impact of school closures in terms of epidemiological and cost effectiveness. Our method assumes that the transmissibility and the severity of the disease are uncertain, and evaluates several closure and reopening strategies that cover a range of thresholds in school-aged prevalence (SAP) and closure durations.

resultsAssuming a willingness to pay per quality adjusted life-year (QALY) threshold equal to the US per capita GDP ($46,000), we found that the cost effectiveness of these strategies is highly dependent on the severity and on a willingness to pay per QALY. For severe pandemics, the preferred strategy couples the earliest closure trigger (0.5% SAP) with the longest duration closure (24 weeks) considered. For milder pandemics, the preferred strategies also involve the earliest closure trigger, but are shorter duration (12 weeks for low transmission rates and variable length for high transmission rates).

conclusionsThese findings highlight the importance of obtaining early estimates of pandemic severity and provide guidance to public health decision-makers for effectively tailoring school closures strategies in response to a newly emergent influenza pandemic.

Indexed as

Decision Support TechniquesInfluenza A Virus, H1N1 SubtypeAdolescentChildChild, PreschoolComputer SimulationCost-Benefit AnalysisHealth PolicyHumansInfluenza, HumanModels, EconomicModels, TheoreticalPandemicsSchoolsTexasYoung Adult

Identifiers

PMID22713694
PMCPMC3495022
OpenAlexW2125130311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.