ArticleBiophysical journal2012
Analytical tools to distinguish the effects of localization error, confinement, and medium elasticity on the velocity autocorrelation function.
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- CRISPR-Cas-based live cell imaging of genome dynamics.Nature reviews. Genetics · 2026Review
- Harnessing confinement effect and interpretable machine learning to predict alkane diffusion in zeolite catalysts.Nature communications · 2026Article
- Gene loci fluctuations reveal bacterial chromosome dynamical organization.Communications biology · 2025Article
- Chemical propulsion of hemozoin crystal motion in malaria parasites.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Practical considerations for accurate estimation of diffusion parameters from single-particle tracking in living cells.The Journal of chemical physics · 2025Article
- Single-particle tracking of genetically encoded nanoparticles: Optimizing expression for cytoplasmic diffusion studies.Biophysical journal · 2025Article
- Practical considerations for accurate estimation of diffusion parameters from single-particle tracking in living cells.bioRxiv : the preprint server for biology · 2025Article
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- Trajectory Analysis in Single-Particle Tracking: From Mean Squared Displacement to Machine Learning Approaches.International journal of molecular sciences · 2024Review
- Polysome collapse and RNA condensation fluidize the cytoplasm.Molecular cell · 2024Article
- Cytoplasmic fluidization contributes to breaking spore dormancy in fission yeast.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- ATP-induced cross-linking of a biomolecular condensate.Biophysical journal · 2024Article
- Burst of hopping trafficking correlated reversible dynamic interactions between lipid droplets and mitochondria under starvation.Exploration (Beijing, China) · 2023Article
- Leveraging polymer modeling to reconstruct chromatin connectivity from live images.Biophysical journal · 2023Article
- Vast heterogeneity in cytoplasmic diffusion rates revealed by nanorheology and Doppelgänger simulations.Biophysical journal · 2023Article
- Diffusion and distal linkages govern interchromosomal dynamics during meiotic prophase.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes.Entropy (Basel, Switzerland) · 2021Article
- Single-Particle Tracking Reveals Anti-Persistent Subdiffusion in Cell Extracts.Entropy (Basel, Switzerland) · 2021Article
- Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299.Communications biology · 2021Article
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5 authors.
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Abstract
Single particle tracking is a powerful technique for investigating the dynamic behavior of biological molecules. However, many of the analytical tools are prone to generate results that can lead to mistaken interpretations of the underlying transport process. Here, we explore the effects of localization error and confinement on the velocity autocorrelation function, Cυ. We show that calculation of Cυ across a range of discretizations can distinguish the effects of localization error, confinement, and medium elasticity. Thus, under certain regimes, Cυ can be used as a diagnostic tool to identify the underlying mechanism of anomalous diffusion. Finally, we apply our analysis to experimental data sets of chromosomal loci and RNA-protein particles in Escherichia coli.
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