ArticleBJOG : an international journal of obstetrics and gynaecology2012
The effect of alcohol binge drinking in early pregnancy on general intelligence in children.
Article in BJOG : an international journal of obstetrics and gynaecology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Prevalence and Patterns of Prenatal Alcohol Exposure in Australian Cohort and Cross-Sectional Studies: A Systematic Review of Data Collection Approaches.International journal of environmental research and public health · 2022Pooled it
- A Meta-Analysis of Stressors from the Total Environment Associated with Children's General Cognitive Ability.International journal of environmental research and public health · 2020Pooled it
- Contributions of a Child's Built, Natural, and Social Environments to Their General Cognitive Ability: A Systematic Scoping Review.PloS one · 2016Pooled it
- Clinical Features of Typically Developing Children with and without Prenatal Alcohol Exposure.The Journal of pediatrics · 2025Article
- Neurological Disorders Induced by Drug Use: Effects of Adolescent and Embryonic Drug Exposure on Behavioral Neurodevelopment.International journal of molecular sciences · 2024Review
- Reducing the Prevalence of Alcohol-Exposed Pregnancies in the United States: A Simulation Modeling Study.Medical decision making : an international journal of the Society for Medical Decision Making · 2022Article
- Impact of prenatal alcohol exposure on neurodevelopmental outcomes: a systematic review.Health psychology and behavioral medicine · 2022Review
- Behavioral Problems at Age 11 Years After Prenatal and Postnatal Exposure to Acetaminophen: Parent-Reported and Self-Reported Outcomes.American journal of epidemiology · 2021Article
- Associations of birth size, infancy, and childhood growth with intelligence quotient at 5 years of age: a Danish cohort study.The American journal of clinical nutrition · 2020Article
- Impact of gestational age on child intelligence, attention and executive function at age 5: a cohort study.BMJ open · 2019Article
- Is breast feeding associated with offspring IQ at age 5? Findings from prospective cohort: Lifestyle During Pregnancy Study.BMJ open · 2019Observational
- Cognitive function among schoolchildren in Lebanon: association with maternal alcohol drinking and smoking during pregnancy and domestic use of detergents and pesticides during childhood.Environmental science and pollution research international · 2019Article
- Prenatal Exposure to Perfluoroalkyl Substances and IQ Scores at Age 5; a Study in the Danish National Birth Cohort.Environmental health perspectives · 2018Article
- Maternal Thyroid Function in Early Pregnancy and Neuropsychological Performance of the Child at 5 Years of Age.The Journal of clinical endocrinology and metabolism · 2018Article
- The Early Developmental Outcomes of Prenatal Alcohol Exposure: A Review.Frontiers in neurology · 2018Review
- Impact of Prenatal and Subsequent Adult Alcohol Exposure on Pro-Inflammatory Cytokine Expression in Brain Regions Necessary for Simple Recognition Memory.Brain sciences · 2017Article
- Alcohol and fertility: how much is too much?Fertility research and practice · 2017Review
- Pre-conception and prenatal alcohol exposure from mothers and fathers drinking and head circumference: results from the Norwegian Mother-Child Study (MoBa).Scientific reports · 2016Article
- "Did you ever drink more?" A detailed description of pregnant women's drinking patterns.BMC public health · 2016Article
- The association of pre-pregnancy alcohol drinking with child neuropsychological functioning.BJOG : an international journal of obstetrics and gynaecology · 2015Article
Corrections and comments
- Commented on by
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- Erratum issued
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the effects of binge alcohol consumption during early pregnancy, including the number of binge episodes and the timing of binge drinking, on general intelligence in 5-year-old children.
designFollow-up study.
settingNeuropsychological testing in four Danish cities 2003-2008. POPULATION: A cohort of 1617 women and their children sampled from the Danish National Birth Cohort.
methodsParticipants were sampled on the basis of maternal alcohol consumption during pregnancy. At 5 years of age the children were tested with six subtests from the Wechsler Preschool and Primary Scale of Intelligence - Revised (WPPSI-R). Parental education, maternal IQ, prenatal maternal smoking, the child's age at testing, the gender of the child, and tester were considered core confounding factors, whereas the full model also controlled for prenatal maternal average alcohol intake, maternal age, maternal pre-pregnancy body mass index (BMI), parity, home environment, postnatal parental smoking, health status, and indicators for hearing and vision impairment.
main outcome measureWPPSI-R.
resultsThere were no systematic or significant differences in general intelligence between children of mothers reporting binge drinking and children of mothers with no binge episodes, except that binge drinking in gestational weeks 1-2 significantly reduced the risk of low, full-scale IQ (OR 0.54; 95% CI 0.31-0.96) when adjusted for core confounding factors. The results were otherwise not statistically significantly related to the number of binge episodes (with a maximum of 12) and timing of binge drinking.
conclusionsWe found no systematic association between binge drinking during early pregnancy and child intelligence. However, binge drinking reduced the risk of low, full-scale IQ in gestational weeks 1-2. This finding may be explained by residual confounding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.