ArticleInternational wound journal2013
Risk factors for recurrence of diabetic foot ulcers: prospective follow-up analysis in the Eurodiale subgroup.
Article in International wound journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 81 papers, 8 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Randomised Control Trial to Measure the Effectiveness of Combined Modulated Ultrasound and Electric Current Stimulation in Treating Diabetic Foot Ulcers
Effect of Self-structured Foot Exercise on the Incidence of Plantar Foot Diabetic Ulcer Recurrence Post Healing at Least One Month
Who cites it
81 citing papers in PubMed, 8 syntheses or guidelines pooled it, 204 citations in OpenAlex.
- Risk factors associated with the recurrence of diabetic foot ulcers: A meta-analysis.PloS one · 2025Pooled it
- [Construction and preliminary validation of a risk prediction model for the recurrence of diabetic foot ulcer in diabetic patients].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Pooled it
- Influencing factors for the recurrence of diabetic foot ulcers: A meta-analysis.International wound journal · 2023Pooled it
- Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes.The Cochrane database of systematic reviews · 2021Pooled it
- Efficacy of hyperbaric oxygen therapy for diabetic foot ulcer, a systematic review and meta-analysis of controlled clinical trials.Scientific reports · 2021Pooled it
- Risk factors for the recurrence of diabetic foot ulcers among diabetic patients: a meta-analysis.International wound journal · 2019Pooled it
- Health-related quality of life among adults living with diabetic foot ulcers: a meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Pooled it
- Efficacy of Biophysical Energies on Healing of Diabetic Skin Wounds in Cell Studies and Animal Experimental Models: A Systematic Review.International journal of molecular sciences · 2019Pooled it
- Perilesional injections of human platelet lysate versus platelet poor plasma for the treatment of diabetic foot ulcers: A double-blinded prospective clinical trial.International wound journal · 2023Trial
- Trial
- Systolic blood pressure variability and lower extremity amputation in a non-elderly population with diabetes.Diabetes research and clinical practice · 2016Trial
- Prevention of recurrent foot ulcers with plantar pressure-based in-shoe orthoses: the CareFUL prevention multicenter randomized controlled trial.Diabetes care · 2014Trial
- How Do Poverty, Insurance, and Government Assistance Impact Diabetic Foot Ulcer Outcomes? A Scoping Review.Diabetes/metabolism research and reviews · 2026Article
- Evaluating the effectiveness and acceptability of an animated educational tool for diabetic foot care: A randomized controlled trial and mixed-methods study in patients with active, in-remission and high-risk diabetic foot disease.Journal of diabetes investigation · 2026Article
- Paddy Farmers' Perspectives on Foot Care, their Modalities for Prevention of Foot Injuries- A Community-based Qualitative Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Article
- A systematic review and meta-analysis on prevalence and risk factors for diabetic foot ulcers in Nepal.Annals of medicine and surgery (2012) · 2026Article
- Predicting the diabetic foot in patients with type 2 diabetes mellitus based on machine learning.Biomedical engineering online · 2026Article
- Severity-Stratified Healing Outcomes of Nurse-Managed Negative Pressure Wound Therapy in Diabetic Foot Ulcers: A Prospective Comparative Cohort Study.Nursing research and practice · 2026Article
- Precision nutrition in diabetic foot ulcers: multimodal artificial intelligence for personalized metabolic management.Frontiers in nutrition · 2026Review
- Interpretable machine learning model for predicting recurrence in patients with diabetic foot ulcers.BMJ open diabetes research & care · 2025Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Few studies have examined factors associated with diabetic foot ulcer (DFU) recurrence. Using data from patients enrolled in the prospective Eurodiale DFU study, we investigated the frequency of and risk factors for DFU recurrence after healing during a 3-year follow-up period. At our site, 93 Eurodiale-enrolled patients had a healed DFU. Among these, 14 were not alive; of the remaining 79 patients we enrolled 73 in this study. On entry to the Eurodiale study, we assessed demographic factors (age, sex and distance from hospital); diabetes-related factors [duration, and glycated haemoglobin (HbA1c) levels]; comorbidities (obesity, renal failure, smoking and alcohol abuse) and DFU-related factors [peripheral arterial disease, ulcer infection, C-reactive protein (CRP) and; foot deformities]. During the 3-year follow-up period, a DFU had recurred in 42 patients (57.5%). By stepwise logistic regression of findings at initial DFU presentation, the significant independent predictors for recurrence were plantar ulcer location [odds ratio (OR) 8.62, 95% confidence interval (CI) 2.2-33.2]; presence of osteomyelitis (OR 5.17, 95% CI 1.4-18.7); HbA1c > 7.5% ([DCCT], OR 4.07, 95% CI 1.1-15.6) and CRP > 5 mg/l (OR 4.27, 95% CI 1.2-15.7). In these patients with a healed DFU, the majority had a recurrence of DFU during a 3-year follow-up period, despite intensive foot care. The findings at diagnosis of the initial DFU were independent risk factors associated with ulcer recurrence (plantar location, bone infection, poor diabetes control and elevated CRP) and define those at high risk for recurrence, but may be amenable to targeted interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.