ArticleMolecular plant-microbe interactions : MPMI2012
Genome sequencing and mapping reveal loss of heterozygosity as a mechanism for rapid adaptation in the vegetable pathogen Phytophthora capsici.
Article in Molecular plant-microbe interactions : MPMI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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136 citing papers in PubMed, 274 citations in OpenAlex.
- Transcriptional programs controlling sporulation in Phytophthora respond to nutrition, humidity, and cryptochrome-mediated light signals.PLoS pathogens · 2026Article
- Fungal DNA damage repair: from model to driver of virulence and AMR.Bioscience reports · 2026Review
- Whole-Genome Sequencing of PathogenicJournal of fungi (Basel, Switzerland) · 2026Article
- Chromosome-scale assembly and annotation of Phytophthora capsici isolate BYA5.Scientific data · 2026Article
- Phytophthora capsici carries and differentially expresses genes for the RNA interference pathway.PloS one · 2026Article
- Metagenomics of the MAST-3 stramenopile,Microbial genomics · 2025Article
- Phytophthora Avr3a-Like Effectors Target and Inhibit Cinnamyl Alcohol Dehydrogenase CAD5 to Suppress Plant Immunity.Molecular plant pathology · 2025Article
- Profiling the Genomes and Secreted Effector Proteins inJournal of fungi (Basel, Switzerland) · 2025Article
- A core Plasmopara viticola effector attenuates the DNA-binding activity of bZIP transcription factor to compromise plant immunity.The Plant journal : for cell and molecular biology · 2025Article
- Transcriptome analysis provides new insights into the resistance of pepper to Phytophthora capsici infection.BMC genomics · 2025Article
- Recombination landscape and karyotypic variations revealed by linkage mapping in the grapevine downy mildew pathogen Plasmopara viticola.G3 (Bethesda, Md.) · 2025Article
- Genome Assembly, Polishing, and Analysis of the Chytrid Batrachochytrium salamandrivorans.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Cultivable root endophytic fungi associated with Acrocomia aculeata and its antagonistic activity against phytopathogenic oomycetes.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Genome-Wide Identification and Analysis of Gene Family of Carbohydrate-Binding Modules inInternational journal of molecular sciences · 2024Article
- Exploring the Global Trends ofSaudi journal of biological sciences · 2024Review
- Functional genomics identifies a small secreted protein that plays a role during the biotrophic to necrotrophic shift in the root rot pathogenFrontiers in plant science · 2024Article
- Transcriptomic analysis reveals pathogenicity mechanisms ofFrontiers in microbiology · 2024Article
- PcLRR-RK3, an LRR receptor kinase is required for growth andMycology · 2024Article
- MarFERReT, an open-source, version-controlled reference library of marine microbial eukaryote functional genes.Scientific data · 2023Article
- Article
76 more citing papers are in PubMed but not listed here.
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Authors and funding
35 authors at 14 institutions in 6 countries.
Funding
Abstract
The oomycete vegetable pathogen Phytophthora capsici has shown remarkable adaptation to fungicides and new hosts. Like other members of this destructive genus, P. capsici has an explosive epidemiology, rapidly producing massive numbers of asexual spores on infected hosts. In addition, P. capsici can remain dormant for years as sexually recombined oospores, making it difficult to produce crops at infested sites, and allowing outcrossing populations to maintain significant genetic variation. Genome sequencing, development of a high-density genetic map, and integrative genomic or genetic characterization of P. capsici field isolates and intercross progeny revealed significant mitotic loss of heterozygosity (LOH) in diverse isolates. LOH was detected in clonally propagated field isolates and sexual progeny, cumulatively affecting >30% of the genome. LOH altered genotypes for more than 11,000 single-nucleotide variant sites and showed a strong association with changes in mating type and pathogenicity. Overall, it appears that LOH may provide a rapid mechanism for fixing alleles and may be an important component of adaptability for P. capsici.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.