Evidence map›Paper›PMID 22711980›Full record

ArticleMaterials science & engineering. C, Materials for biological applications2012

Antimicrobial Particulate Silver Coatings on Stainless Steel Implants for Fracture Management.

Paul Devasconcellos, Susmita Bose, Haluk Beyenal, Amit Bandyopadhyay, Lewis G Zirkle

Abstract read
In one paragraph

Article in Materials science & engineering. C, Materials for biological applications, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Silver nanoparticle deposited implants to treat osteomyelitis.Journal of biomedical materials research. Part B, Applied biomaterials · 2018
    Article
  14. Article
  15. Article
  16. Mechanical degradation of TiO2 nanotubes with and without nanoparticulate silver coating.Journal of the mechanical behavior of biomedical materials · 2016
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul DevasconcellosW.M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA USA.
Susmita Bose
Haluk Beyenal
Amit Bandyopadhyay
Lewis G Zirkle

Funding

Resorbable Calcium Phosphate Ceramics for Bone Graft.R01EB007351 · NIBIB · WASHINGTON STATE UNIVERSITY · PI BOSE, SUSMITA · 2008 to 2011
$1.4M
NIBIB NIH HHS R01 EB007351
6 · The paper itself

Abstract

We have used particulate silver coating on stainless steel to prevent in vivo bacterial infection. Stainless steel is commonly used as an implant material for fracture management. The antimicrobial use of silver has been well documented and studied, therefore the novelty of this research is the use of a particulate coating as well as facing the real world challenges of a fracture repair implant. The variable parameters for applying the coating were time of deposition, silver solution concentration, voltage applied, heat treatment temperature between 400 to 500 °C and time. The resultant coating is shown to be non-toxic to human osteoblasts using an MTT assay for proliferation and SEM images for morphology. In vitro silver release studies of various treatments were done using simulated body fluid. The bactericidal effects were tested by challenging the coatings with P. aeruginosa in a bioreactor and compared against uncoated stainless steel. A 13-fold reduction in bacteria was observed at 24 hours and proved to be statistically significant.

Identifiers

PMID22711980
PMCPMC3375829

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.