ArticleProceedings of the National Academy of Sciences of the United States of America2012
ZmCCT and the genetic basis of day-length adaptation underlying the postdomestication spread of maize.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers, 1 of them a synthesis that pooled it.
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174 citing papers in PubMed, 1 synthesis or guideline pooled it, 339 citations in OpenAlex.
- CCT domain-containing genes in cereal crops: flowering time and beyond.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Pooled it
- A domestication-selected CIPK-MYB-HAK module improves salt tolerance in modern maize.Nature plants · 2026Article
- Multimodal single cell analysis reveals a link between flowering and leaf initiation.bioRxiv : the preprint server for biology · 2026Article
- Optimized Cas-SF01 gene-editing toolbox shortens flowering timing in commercial maize inbred JING724.Journal of integrative plant biology · 2026Article
- Designed Alleles of ZmRap2.7 Decouple the Trade-Off Between Early Flowering and Yield Penalty.Plant biotechnology journal · 2026Article
- Hybrid origin and phenotype evolution of the modern maize.Journal of integrative plant biology · 2026Review
- Identification of a pleiotropic QTL and candidate genes underlying ear traits of maize (Zea mays L.) through controlling the activity of inflorescence meristem.BMC genomics · 2026Article
- Constitutive overexpression of GRF21, a 14-3-3 family protein, delays flowering time in maize (Zea mays).BMC plant biology · 2026Article
- Article
- Genome and transcriptome analyses reveal parallel altitude adaptation in Chenopodium.Genome biology · 2026Article
- DNAwhisper: An Integrated Deep Learning Pyramidal Framework for Multi-Trait Genomic Prediction and Adaptive Marker Prioritisation.Plant biotechnology journal · 2026Article
- Dynamic and cell-type specific transcriptional reprogramming underlies the floral transition in the maize shoot apical meristem.Genome biology · 2026Article
- Integrated GWAS and Fst analysis identify flowering-time regulatory genes in maize.The plant genome · 2026Article
- Transposable element-mediated DNA methylation of the NAC20 and NAC26 promoters led to a maternal effect on grain filling.Journal of integrative plant biology · 2026Article
- A Trypsin-Like Serine Protease ZmNAL1a Fine-Tunes Maize Floral Transition and Flowering Time.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Predicted protein 3D structures provide essential insights into the genetic architecture underlying phenotypic diversity in maize.Genome research · 2026Article
- Unlocking tropical adaptation: novel flowering time genes implicate JA and ROS signaling in maize.BMC plant biology · 2026Article
- Integrative QTL mapping and RNA-seq unravel the genetic architecture and candidate genes for ear shank length in a large maize-teosinte population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Ensemble AnalySis with Interpretable Genomic Prediction (EasiGP): Computational tool for interpreting ensembles of genomic prediction models.The plant genome · 2025Article
- Structural Variants Contribute to Phenotypic Variation in Maize.Molecular ecology · 2025Article
114 more citing papers are in PubMed but not listed here.
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11 authors at 6 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Teosinte, the progenitor of maize, is restricted to tropical environments in Mexico and Central America. The pre-Columbian spread of maize from its center of origin in tropical Southern Mexico to the higher latitudes of the Americas required postdomestication selection for adaptation to longer day lengths. Flowering time of teosinte and tropical maize is delayed under long day lengths, whereas temperate maize evolved a reduced sensitivity to photoperiod. We measured flowering time of the maize nested association and diverse association mapping panels in the field under both short and long day lengths, and of a maize-teosinte mapping population under long day lengths. Flowering time in maize is a complex trait affected by many genes and the environment. Photoperiod response is one component of flowering time involving a subset of flowering time genes whose effects are strongly influenced by day length. Genome-wide association and targeted high-resolution linkage mapping identified ZmCCT, a homologue of the rice photoperiod response regulator Ghd7, as the most important gene affecting photoperiod response in maize. Under long day lengths ZmCCT alleles from diverse teosintes are consistently expressed at higher levels and confer later flowering than temperate maize alleles. Many maize inbred lines, including some adapted to tropical regions, carry ZmCCT alleles with no sensitivity to day length. Indigenous farmers of the Americas were remarkably successful at selecting on genetic variation at key genes affecting the photoperiod response to create maize varieties adapted to vastly diverse environments despite the hindrance of the geographic axis of the Americas and the complex genetic control of flowering time.
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