SynthesisHuman brain mapping2013
The centre of the brain: topographical model of motor, cognitive, affective, and somatosensory functions of the basal ganglia.
Synthesis in Human brain mapping, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 11 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Mentalizing About Dynamic Social Action Sequences Is Supported by the Cerebellum, Basal Ganglia, and Neocortex: A Meta-Analysis of Activation and Connectivity.Human brain mapping · 2024Pooled it
- The neuroanatomy of developmental language disorder: a systematic review and meta-analysis.Nature human behaviour · 2024Pooled it
- Cerebral Volumetric Correlates of Apathy in Alzheimer's Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort.Journal of Alzheimer's disease : JAD · 2022Pooled it
- Basal ganglia lateralization in different types of reward.Brain imaging and behavior · 2020Pooled it
- Spatial migration of human reward processing with functional development: Evidence from quantitative meta-analyses.Human brain mapping · 2020Pooled it
- Dissociations of cognitive inhibition, response inhibition, and emotional interference: Voxelwise ALE meta-analyses of fMRI studies.Human brain mapping · 2018Pooled it
- Brain areas associated with numbers and calculations in children: Meta-analyses of fMRI studies.Developmental cognitive neuroscience · 2018Pooled it
- Is the voice an auditory face? An ALE meta-analysis comparing vocal and facial emotion processing.Social cognitive and affective neuroscience · 2018Pooled it
- The neural basis of sex differences in sexual behavior: A quantitative meta-analysis.Frontiers in neuroendocrinology · 2016Pooled it
- Contribution of insula in Parkinson's disease: A quantitative meta-analysis study.Human brain mapping · 2016Pooled it
- Psychosocial versus physiological stress - Meta-analyses on deactivations and activations of the neural correlates of stress reactions.NeuroImage · 2015Pooled it
- The role of the striatum in effort-based decision-making in the absence of reward.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Trial
- Unlearning chronic pain: A randomized controlled trial to investigate changes in intrinsic brain connectivity following Cognitive Behavioral Therapy.NeuroImage. Clinical · 2014Trial
- The genetic overlap between schizophrenia and major depression with cognitive function.Molecular psychiatry · 2026Article
- Disrupted Functional Network Organization in Crohn's Disease: Interoceptive Alterations Linked to Anxiety.CNS neuroscience & therapeutics · 2026Article
- Neonatal Cerebrovascular Stability Index and Oxygenation With 3-Month Neurodevelopmental Outcomes.JACC. Advances · 2026Article
- The Cognitive-Affective Social Processing and Emotion Regulation (CASPER) model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Structural and pragmatic language skills in school-age children relate to resting state functional connectivity.Brain imaging and behavior · 2025Article
- Interaction Between Oxytocin and Dopamine Signaling: Focus on the Striatum.International journal of molecular sciences · 2025Review
- Impact of impulsivity on the relationship of the brain structures with school performance.NPJ science of learning · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The basal ganglia have traditionally been viewed as motor processing nuclei; however, functional neuroimaging evidence has implicated these structures in more complex cognitive and affective processes that are fundamental for a range of human activities. Using quantitative meta-analysis methods we assessed the functional subdivisions of basal ganglia nuclei in relation to motor (body and eye movements), cognitive (working-memory and executive), affective (emotion and reward) and somatosensory functions in healthy participants. We document affective processes in the anterior parts of the caudate head with the most overlap within the left hemisphere. Cognitive processes showed the most widespread response, whereas motor processes occupied more central structures. On the basis of these demonstrated functional roles of the basal ganglia, we provide a new comprehensive topographical model of these nuclei and insight into how they are linked to a wide range of behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.