Evidence map›Paper›PMID 22711611›Full record

ArticleFamilial cancer2012

Outcomes of a systems-level intervention offering breast cancer risk assessments to low-income underserved women.

Darren Mays, McKane E Sharff, Tiffani A DeMarco, Bernice Williams, Beth Beck, Vanessa B Sheppard, Beth N Peshkin, Jennifer Eng-Wong, Kenneth P Tercyak

Registry-linked trialAbstract read
In one paragraph

Article in Familial cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03511690 (Testing an Intelligent Tutoring System Intervention to Enhance Genetic Risk Assessment in Underserved Blacks and Latinas at Risk of Hereditary Breast Cancer), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03511690 nacompletednot on this mapstarted 2017, after this paper: background citation

Testing an Intelligent Tutoring System Intervention to Enhance Genetic Risk Assessment in Underserved Blacks and Latinas at Risk of Hereditary Breast Cancer

TypeinterventionalSponsorGeorgetown UniversityRan2017 to 2022Enrolled95ConditionsHereditary Breast and Ovarian CancerArmsBRCA-Gist
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 25 citations in OpenAlex.

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  13. Understanding Medical Mistrust in Black Women at Risk of BRCA 1/2 Mutations.Journal of health disparities research and practice · 2019
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  19. Genomic Disparities in Breast Cancer Among Latinas.Cancer control : journal of the Moffitt Cancer Center · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Darren MaysDivision of Health Outcomes and Health Behaviors, Department of Oncology, Lombardi Comprehensive Cancer, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007, USA.
McKane E Sharff
Tiffani A DeMarco
Bernice Williams
Beth Beck
Vanessa B Sheppard
Beth N Peshkin
Jennifer Eng-Wong
Kenneth P Tercyak
Georgetown University Medical Center · USGeorgetown University · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
Parent Communication of BRCA1/2 Test Results to ChildrenR01HG002686 · NHGRI · GEORGETOWN UNIVERSITY · PI TERCYAK, KENNETH · 2003 to 2009
$3.1M
NCI NIH HHS P30 CA051008NHGRI NIH HHS R01 HG002686NHGRI NIH HHS R01HG002686-S1
6 · The paper itself

Abstract

Hereditary breast and ovarian cancer risk assessments (CRAs) are underutilized by low-income and racial/ethnic minority women, potentially exacerbating cancer-related disparities observed within these populations. We deployed and evaluated a systems-level intervention designed to identify patients potentially at-risk for hereditary breast/ovarian cancer, refer them for CRAs, and facilitate CRA utilization at an urban community-based breast health care center. Cancer family history forms were completed by patients seen at the center during an 18-month period and reviewed by staff for CRA eligibility against published referral criteria. A patient navigator educated eligible patients about the benefits of CRA, navigating interested patients to this service. CRA-specific patient interest and utilization outcomes are reported. In total, 94.7 % of all patients (n = 2,436) completed forms and 65 patients (2.7 %) met CRA eligibility criteria. Most eligible patients (72.3 %) were interested in CRA. Interested patients had a greater risk for hereditary breast/ovarian cancer (i.e., more affected relatives, greater objective risk scores) than uninterested patients: 57.4 % scheduled a CRA appointment and 51.9 % of scheduled patients utilized CRAs. Patients scheduling a CRA were contacted in less time and required fewer follow-up contacts by the patient navigator, and were more likely to be African American, than those who declined a CRA or were lost to follow-up (all p's ≤ .05). The systems-level intervention successfully identified patients eligible for CRA and linked interested and at-risk patients with CRA resources. More intensive patient navigation addressing the unique barriers encountered within this population may be required to enhance utilization.

Indexed as

Genetic CounselingVulnerable PopulationsBlack or African AmericanBreast NeoplasmsDistrict of ColumbiaFamilyFemaleHumansMedical History TakingMiddle AgedOvarian NeoplasmsRisk AssessmentUrban Health Services

Identifiers

PMID22711611
PMCPMC3521596
OpenAlexW1969088122

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.