Evidence map›Paper›PMID 22710929›Full record

SynthesisInternational journal of obesity (2005)2013

Obesity and endometrial cancer survival: a systematic review.

H Arem, M L Irwin

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of obesity (2005), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Weight Loss Randomized Intervention Trials in Female Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016
    Pooled it
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  11. Observational
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  16. Review
  17. Impact of electronic medical record utilization on obesity screening and intervention for obese patients with endometrial cancer.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024
    Article
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

H AremDepartment of Chronic Disease Epidemiology, Yale University, School of Public Health, New Haven, CT 06520, USA. Hannah.Arem@yale.edu
M L Irwin

Funding

Yale/NCI Cooperative Training Program in Cancer EpidemiologyT32CA105666 · NCI · YALE UNIVERSITY · PI MA, XIAOMEI · 2008 to 2012
$603k
NCI NIH HHS T32 CA105666
6 · The paper itself

Abstract

Although it is known that obesity increases the risk of endometrial cancer and is linked to higher mortality rates in the general population, the association between obesity and mortality among endometrial cancer survivors is unclear. We performed a medline search using exploded Mesh keywords 'endometrial neoplasms/' and ('body mass index/' or 'obesity/') and ('survival analysis/' or 'mortality/' or (survivor* or survival*).mp.). We also inspected bibliographies of relevant papers to identify related publications. Our search criteria yielded 74 studies, 12 of which met inclusion criteria. Four of the included studies reported a statistically or marginally significant association between obesity and higher all cause mortality among endometrial cancer survivors after multivariate adjustment. The suggestive association between body mass index and higher all cause mortality among women with endometrial cancer was comparable to the magnitude of association reported in prospective studies of healthy women. Of the five studies that examined progression-free survival and the two studies reporting on disease-specific mortality, none reported an association with obesity. Future studies are needed to understand disease-specific mortality, the importance of obesity-onset timing and whether mechanisms of obesity-related mortality in this population of women differ from those of the general population.

Indexed as

Women's HealthAdultAge of OnsetBody Mass IndexDisease-Free SurvivalEndometrial NeoplasmsFemaleHumansMiddle AgedObesityRisk FactorsSedentary BehaviorSurvival AnalysisUnited States

Identifiers

PMID22710929
PMCPMC3774112

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.