SynthesisClinical biochemistry2012
Effectiveness of practices to reduce blood culture contamination: a Laboratory Medicine Best Practices systematic review and meta-analysis.
Synthesis in Clinical biochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05686577 (Comment Diminuer Les hémocultures Inutiles), which is not on this map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comment Diminuer Les hémocultures Inutiles : Construction et Validation d'un Score prédictif de positivité Des hémocultures en réanimation.
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- American Society for Microbiology evidence-based laboratory medicine practice guidelines to reduce blood culture contamination rates: a systematic review and meta-analysis.Clinical microbiology reviews · 2024Pooled it
- A Laboratory Medicine Best Practices Systematic Review and Meta-analysis of Nucleic Acid Amplification Tests (NAATs) and Algorithms Including NAATs for the Diagnosis ofClinical microbiology reviews · 2019Pooled it
- Effectiveness of Preanalytic Practices on Contamination and Diagnostic Accuracy of Urine Cultures: a Laboratory Medicine Best Practices Systematic Review and Meta-analysis.Clinical microbiology reviews · 2016Pooled it
- Reduction in Blood Culture Contamination Through Use of Initial Specimen Diversion Device.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Trial
- Clinical and Molecular Characteristics ofOpen forum infectious diseases · 2026Article
- In-depth analysis of sampling practice and yield of blood cultures.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Observational
- Taming the contaminants: a quality improvement initiative to minimize blood culture contamination and enhance patient care in a resource-limited setting.BMC microbiology · 2026Article
- Clinician perspectives on blood culture practice and diagnostic stewardship in regional emergency departments.Journal of medical microbiology · 2026Article
- Reducing blood culture contamination in the ED: impact of Kurin Lock® implementation.Infection prevention in practice · 2026Article
- Risk factors for blood culture contamination in a tertiary hospital: a one-year retrospective analysis.BMC infectious diseases · 2026Article
- Diagnostic value of blood culture growth patterns in distinguishing contaminants from pathogens.Journal of clinical microbiology · 2026Article
- A Two-Year Retrospective Study of Blood Cultures in a Secondary Western Greece Healthcare Setting.Microorganisms · 2026Article
- Multiyear experience with blood culture results from a tertiary care hospital in Saudi Arabia: a retrospective study.BMC infectious diseases · 2025Article
- Article
- Blood Culture Contamination and Diagnostic Stewardship: From a Clinical Laboratory Quality Monitor to a National Patient Safety Measure.The journal of applied laboratory medicine · 2025Review
- The trends of blood culture contamination and utilization rates in an LMIC tertiary care center from 2010 to 2022: a call for diagnostic stewardship?Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- The American Society for Microbiology collaboration with the CDC Laboratory Medicine Best Practices initiative for evidence-based laboratory medicine.Clinical microbiology reviews · 2024Review
- Low penicillin susceptibility inMicrobiology spectrum · 2024Article
- A Five-Bundle Intervention to Improve Blood Culture Use in a Tertiary Hospital in Romania.Antibiotics (Basel, Switzerland) · 2024Article
- Microbial growth on temporary pacemaker leads post-TAVR: pathogen spectrum and clinical implications.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesThis article is a systematic review of the effectiveness of three practices for reducing blood culture contamination rates: venipuncture, phlebotomy teams, and prepackaged preparation/collection (prep) kits. DESIGN AND
methodsThe CDC-funded Laboratory Medicine Best Practices Initiative systematic review methods for quality improvement practices were used.
resultsStudies included as evidence were: 9 venipuncture (vs. versus intravenous catheter), 5 phlebotomy team; and 7 prep kit. All studies for venipuncture and phlebotomy teams favored these practices, with meta-analysis mean odds ratios for venipuncture of 2.69 and phlebotomy teams of 2.58. For prep kits 6 studies' effect sizes were not statistically significantly different from no effect (meta-analysis mean odds ratio 1.12).
conclusionsVenipuncture and the use of phlebotomy teams are effective practices for reducing blood culture contamination rates in diverse hospital settings and are recommended as evidence-based "best practices" with high overall strength of evidence and substantial effect size ratings. No recommendation is made for or against prep kits based on uncertain improvement.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.