Evidence map›Paper›PMID 22709809›Full record

ArticleJournal of the Academy of Nutrition and Dietetics2012

Mediterranean diet and cognitive decline in women with cardiovascular disease or risk factors.

Marie-Noël Vercambre, Francine Grodstein, Claudine Berr, Jae H Kang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Academy of Nutrition and Dietetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 10 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 10 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Mediterranean diet and cognitive function in older age.Epidemiology (Cambridge, Mass.) · 2013
    Trial
  12. Trial
  13. Trial
  14. Ferroptotic neurodegeneration and diet: a narrative review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marie-Noël VercambreFoundation for Public Health, Mutuelle Generale de l’Education Nationale (MGEN), Paris, France.
Francine Grodstein
Claudine Berr
Jae H Kang
Mutuelle Générale de l'Éducation Nationale · FR

Funding

TRIAL OF ANTIOXIDANT THERAPY OF CVD IN WOMENR01HL046959 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MANSON, JOANN ELISABETH · 1993 to 2005
$3.6M
TRIALS OF PREVENTION OF COGNITIVE DECLINE IN WOMEN AND MR01AG015933 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI GRODSTEIN, FRANCINE · 1998 to 2007
$2.4M
NHLBI NIH HHS HL046959NHLBI NIH HHS R01 HL046959NIA NIH HHS AG15933NIA NIH HHS R01 AG015933
6 · The paper itself

Abstract

backgroundCardiovascular disease and vascular risk factors increase rates of cognitive impairment, but very little is known regarding prevention in this high-risk group. The heart-healthy Mediterranean-type dietary pattern may beneficially influence both vascular and cognitive outcomes.

objectivesWe examined the association between Mediterranean-style diet and cognitive decline in women with prevalent vascular disease or ≥3 coronary risk factors. DESIGN/PARTICIPANTS/

settingProspective cohort study among 2,504 women participants in the Women's Antioxidant Cardiovascular Study (WACS), a cohort of female health professionals. Adherence to a Mediterranean-style diet was determined at WACS baseline (1995-1996) using a 0- to 9-point scale with higher scores indicating higher adherence. In 1998-2000, participants aged ≥65 years underwent a telephone cognitive battery including five tests of global cognition, verbal memory, and category fluency. Tests were administered three additional times across 5.4 years. STATISTICAL ANALYSES PERFORMED: We used multivariable-adjusted generalized linear models for repeated measures to compare the annual rates of cognitive score changes across tertiles of Mediterranean diet score, as assessed at WACS baseline.

resultsIn both basic- and multivariable-adjusted models, consuming a Mediterranean-style diet was not related to cognitive decline. No effect modification was detected by age, education, depression, cardiovascular disease severity at WACS baseline, or level of cognition at initial assessment.

conclusionsIn women at higher risk of cognitive decline due to vascular disease or risk factors, adherence to a Mediterranean-style diet was not associated with subsequent 5-year cognitive change.

Indexed as

Diet, MediterraneanMental HealthAgedAged, 80 and overCardiovascular DiseasesCognition DisordersCohort StudiesFemaleFruitHumansLinear ModelsProspective StudiesRisk FactorsVegetablesWomen's Health

Identifiers

PMID22709809
PMCPMC3378990
OpenAlexW2166913608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.