Evidence map›Paper›PMID 22709668›Full record

ArticleBMC research notes2012

Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes.

Igor K Voukeng, Victor Kuete, Jean P Dzoyem, Aimé G Fankam, Jaures A K Noumedem, Jules R Kuiate, Jean-Marie Pages

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 84 citations in OpenAlex.

  1. Evaluation of antibacterial efficacy of garlic (Journal of advanced veterinary and animal research · 2023
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  9. Antibacterial and Antibiotic Modifying Potential of Crude Extracts, Fractions, and Compounds fromEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
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  12. TheScientificWorldJournal · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Igor K VoukengDepartment of Biochemistry, Faculty of science, University of Dschang, P,O, Box 67, Dschang, Cameroon, Africa.
Victor Kuete
Jean P Dzoyem
Aimé G Fankam
Jaures A K Noumedem
Jules R Kuiate
Jean-Marie Pages
Université de Dschang · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present work was designed to evaluate the antibacterial properties of the methanol extracts of eleven selected Cameroonian spices on multi-drug resistant bacteria (MDR), and their ability to potentiate the effect of some common antibiotics used in therapy.

resultsThe extract of Cinnamomum zeylanicum against Escherichia coli ATCC 8739 and AG100 strains showed the best activities, with the lowest minimal inhibitory concentration (MIC) of 64 μg/ml. The extract of Dorstenia psilurus was the most active when tested in the presence of an efflux pump inhibitor, phenylalanine Arginine-β- Naphtylamide (PAβN), a synergistic effect being observed in 56.25 % of the tested bacteria when it was combined with erythromycin (ERY).

conclusionThe present work evidently provides information on the role of some Cameroonian spices in the fight against multi-resistant bacteria.

Indexed as

SpicesAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacteriaBacterial ProteinsCameroonDrug Resistance, Multiple, BacterialDrug SynergismMethanolMicrobial Sensitivity TestsPlant ExtractsPlants, MedicinalSolventsAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsMethanolPlant ExtractsSolvents

Identifiers

PMID22709668
PMCPMC3438083
OpenAlexW2090525677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.