Evidence map›Paper›PMID 22708924›Full record

ArticleThe British journal of dermatology2013

A multicentre, cross-sectional study on quality of life in patients with cutaneous lupus erythematosus.

R Vasquez, D Wang, Q P Tran, B Adams-Huet, M-M Chren, M I Costner, J B Cohen, V P Werth, B F Chong

Abstract readComparative StudyEvaluation StudyMulticenter Study
In one paragraph

Article in The British journal of dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Drugs for discoid lupus erythematosus.The Cochrane database of systematic reviews · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R VasquezDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
D Wang
Q P Tran
B Adams-Huet
M-M Chren
M I Costner
J B Cohen
V P Werth
B F Chong

Funding

NORTH AND CENTRAL TEXAS CTSA FOR PEDIATRIC RESEARCHUL1RR024982 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$27.9M
UT-Southwestern Clinical and Translational Alliance for Research (UT-STAR) (TL1)UL1TR000451 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2012 to 2012
$6.3M
North and Central Texas Clinical and Translational Science Initiative (KL2)KL2RR024983 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$4.3M
Molecular Markers in Discoid Lupus ErythematousK23AR061441 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHONG, BENJAMIN FRANKLIN · 2012 to 2016
$653k
UT-Southwestern Clinical and Translational Alliance for Research (UT-STAR) (TL1)KL2TR000453 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2012 to 2012
$456k
NCATS NIH HHS KL2 TR000453NCATS NIH HHS UL1 TR000451NCRR NIH HHS KL2 RR024983NCRR NIH HHS UL1 RR024982NIAMS NIH HHS K23 AR061441
6 · The paper itself

Abstract

backgroundA study at the University of Pennsylvania (UPenn) Medical Center demonstrated that quality of life in patients with cutaneous lupus erythematosus (CLE) is negatively impacted. Whether patients with CLE in other geographic locations have similar quality of life is unknown.

objectivesWe sought to compare quality of life indicators between patients with CLE at the University of Texas Southwestern (UTSW) Medical Center at Dallas and those at UPenn.

methodsPatients with CLE (total n=248) at UTSW (n=91) and UPenn (n=157) completed the Skindex-29 +3 and Short Form-36 (SF-36) surveys related to quality of life. Additional information, including demographics, presence of systemic lupus erythematosus (SLE) and disease severity, was collected from UTSW patients with CLE.

resultsMost Skindex-29 + 3 and SF-36 subdomain scores between UTSW and UPenn patients with CLE were similar. However, UTSW patients with CLE were significantly more affected in the functioning and lupus-specific Skindex-29 + 3 domains, and physical functioning, role-physical and general health SF-36 subscales than UPenn patients with CLE (P<0·05). Factors related to poor quality of life in UTSW patients with CLE include sex, income, education, presence of SLE, and skin disease activity.

conclusionsMost quality of life indicators were similar between the two CLE populations. Differences in psychosocial behaviour, and a larger proportion of patients with SLE and females in the UTSW group likely attributed to differences in a minority of Skindex-29+3 and SF-36 subdomains. Capturing data from CLE populations in different locations provides a more thorough picture of the quality of life that patients with CLE experience on a daily basis with special attention to quality of life issues in select patients with CLE.

Indexed as

Quality of LifeActivities of Daily LivingCross-Sectional StudiesEmotionsFemaleHumansIncomeInterpersonal RelationsLupus Erythematosus, CutaneousMaleMiddle AgedMusculoskeletal PainSickness Impact ProfileSurveys and Questionnaires

Identifiers

PMID22708924
PMCPMC3467361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.