ReviewCurrent cardiology reviews2012
Utility of the electrocardiogram in drug overdose and poisoning: theoretical considerations and clinical implications.
Review in Current cardiology reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 46 citations in OpenAlex.
- High Doses of N-Acetyl-P-Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats.Basic & clinical pharmacology & toxicology · 2026Article
- Toxidromes.Nature reviews. Disease primers · 2026Review
- Article
- Biological Variation of Corrected QT and QRS Electrocardiogram Intervals: Interpreting Results of Drug-induced Prolongation.The western journal of emergency medicine · 2025Article
- Left bundle branch block morphology on electrocardiogram after massive diphenhydramine overdose.Toxicology reports · 2025Article
- Prolonged coma due to amitriptyline overdose and genetic polymorphism: a case report.Journal of medical case reports · 2022Article
- Article
- The Relative Risk of Toxico-Clinical Parameters with respect to Poisoning Severity and Outcomes in Patients with Acute Poisoning.Advanced biomedical research · 2022Article
- Prediction of troponin I and N-terminal pro-brain natriuretic peptide levels in acute carbon monoxide poisoning using advanced electrocardiogram analysis, Alexandria, Egypt.Environmental science and pollution research international · 2021Article
- Effects of Cr(VI) exposure on electrocardiogram, myocardial enzyme parameters, inflammatory factors, oxidative kinase, and ATPase of the heart in Chinese rural dogs.Environmental science and pollution research international · 2019Article
- Validation of the Prognostic Utility of the Electrocardiogram for Acute Drug Overdose.Journal of the American Heart Association · 2017Article
- Clinical risk factors for in-hospital adverse cardiovascular events after acute drug overdose.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2015Article
- Level of Serum Enzymes and Electrocardiogram in Healthy Rabbits after Injection of ICD-85 as an Anticancer Agent.Iranian biomedical journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ECG is a rapidly available clinical tool that can help clinicians manage poisoned patients. Specific myocardial effects of cardiotoxic drugs have well-described electrocardiographic manifestations. In the practice of clinical toxicology, classic ECG changes may hint at blockade of ion channels, alterations of adrenergic tone, or dysfunctional metabolic activity of the myocardium. This review will offer a structured approach to ECG interpretation in poisoned patients with a focus on clinical implications and ECG-based management recommendations in the initial evaluation of patients with acute cardiotoxicity.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.