ReviewEssays in biochemistry2012
Discovery of lysine post-translational modifications through mass spectrometric detection.
Review in Essays in biochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Article
- The activity of CobB1 protein deacetylase contributes to nucleoid compaction in Streptomyces venezuelae spores by increasing HupS affinity for DNA.Nucleic acids research · 2024Article
- Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling.iScience · 2024Article
- Beyond metabolic waste: lysine lactylation and its potential roles in cancer progression and cell fate determination.Cellular oncology (Dordrecht, Netherlands) · 2023Review
- New insights into the pathophysiology of methylmalonic acidemia.Journal of inherited metabolic disease · 2023Review
- Site-Specific Detection and Characterization of Ubiquitin Carbamylation.Biochemistry · 2022Article
- A methodology for carbamate post-translational modification discovery and its application inInterface focus · 2021Article
- Discovery of Post-Translational Modifications inMolecules (Basel, Switzerland) · 2021Article
- Measuring acetyl-CoA and acetylated histone turnover in vivo: Effect of a high fat diet.Analytical biochemistry · 2021Article
- Partial proteolysis improves the identification of the extracellular segments of transmembrane proteins by surface biotinylation.Scientific reports · 2020Article
- SUMOylation in α-Synuclein Homeostasis and Pathology.Frontiers in aging neuroscience · 2020Review
- Catalytic activity regulation through post-translational modification: the expanding universe of protein diversity.Advances in protein chemistry and structural biology · 2020Review
- Covalently modified carboxyl side chains on cell surface leads to a novel method toward topology analysis of transmembrane proteins.Scientific reports · 2019Article
- Review
- Utilizing Ion Mobility to Identify Isobaric Post-Translational Modifications: Resolving Acrolein and Propionyl Lysine Adducts by TIMS Mass Spectrometry.International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry · 2018Article
- The identification of carbon dioxide mediated protein post-translational modifications.Nature communications · 2018Article
- Proteomic analysis of chick retina during early recovery from lens‑induced myopia.Molecular medicine reports · 2018Article
- Design of modular dual enzyme-responsive peptides.Biopolymers · 2017Article
- The winding path of protein methylation research: milestones and new frontiers.Nature reviews. Molecular cell biology · 2017Review
- The Glycoprotein B Cytoplasmic Domain Lysine Cluster Is Critical for Varicella-Zoster Virus Cell-Cell Fusion Regulation and Infection.Journal of virology · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The complexity of an organism's proteome is in part due to the diversity of post-translational modifications present that can direct the location and function of a protein. To address the growing interest in characterizing these modifications, mass spectrometric-based proteomics has emerged as one of the most essential experimental platforms for their discovery. In searching for post-translational modifications within a target set of proteins to global surveys of particularly modified proteins within a given proteome, various experimental MS (mass spectrometry) and allied techniques have been developed. Out of 20 naturally encoded amino acids, lysine is essentially the most highly post-translationally modified residue. This chapter provides a succinct overview of such methods for the characterization of protein lysine modifications as broadly classified, such as methylation and ubiquitination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.