Evidence map›Paper›PMID 22707926›Full record

ArticleMicrofluidics and nanofluidics2012

Micro Magnetic Gyromixer for Speeding up Reactions in Droplets.

Yi Zhang, Tza-Huei Wang

Abstract read
In one paragraph

Article in Microfluidics and nanofluidics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yi ZhangDepartment of Biomedical Engineering, Johns Hopkins University. Clark 122, 3400 North Charles Street, Baltimore, MD 21218, USA.
Tza-Huei Wang

Funding

TARGETING EARLY CHANGES FOR NEW SCREENING STRATEGIESP50CA058184 · NCI · JOHNS HOPKINS UNIVERSITY · PI BISWAL, SHYAM · 1992 to 2013
$30.5M
ValidationU54CA151838 · NCI · JOHNS HOPKINS UNIVERSITY · PI SEARSON, PETER C · 2010 to 2014
$11.9M
Multiplexed Detection of Cell Free DNA Biomarkers for CancerR01CA155305 · NCI · JOHNS HOPKINS UNIVERSITY · PI WANG, TZA-HUEI JEFF · 2011 to 2015
$1.7M
Nanobiosensing Method for Point Mutation Detection of CancerR21CA120742 · NCI · JOHNS HOPKINS UNIVERSITY · PI WANG, TZA-HUEI JEFF · 2008 to 2009
$387k
NCI NIH HHS P50 CA058184NCI NIH HHS R01 CA155305NCI NIH HHS R21 CA120742NCI NIH HHS U54 CA151838
6 · The paper itself

Abstract

We report a novel micro magnetic gyromixer designed for accelerating mixing hence reactions in droplets. The gyromixer is fabricated with magnetite-PDMS composite using soft lithography. The mixer spins and balances itself on the droplet surface through the gyroscopic effect, rapidly homogenizing the enclosed reagents by stretching and folding internal fluid streamlines to enhance mixing. We examined the capability of the gyromixer for improving biochemical reactions in droplets by monitoring the biotin-streptavidin binding as a linker in a quantum dot fluorescence resonant energy transfer (QD-FRET) sensing system. The remotely controlled gyromixer exhibits high flexibility and potential for integration in a variety of droplet-based miniaturized total analysis systems (μTAS) to reduce turnaround times.

Identifiers

PMID22707926
PMCPMC3374403

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.