ArticleIndian journal of pharmaceutical sciences2011
Photo- and thermal degradation of piroxicam in aqueous solution.
Article in Indian journal of pharmaceutical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Cyclodextrin-assisted photostabilization of 5-fluorouracil: a combined kinetic and computational investigation.RSC advances · 2025Article
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- Photostability of Topical Agents Applied to the Skin: A Review.Pharmaceutics · 2019Review
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Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
Light and temperature have considerable effect on the degradation of piroxicam in aqueous solutions. The pH and acetate buffer ions also affect the degradation process. The apparent first-order rate constants for the photochemical and thermal degradation of piroxicam have been determined as 2.04-10.01 and 0.86-3.06×10(-3) min(-1), respectively. The first-order plots for the degradation of piroxicam showed good linearity within a range of 20-50% loss of piroxicam at pH 2.0-12.0. The rate-pH profile for the photodegradation of piroxicam is a U-shaped curve and for the thermal degradation a bell-shaped curve in the pH range of 2.0-12.0. The thermal degradation of piroxicam was maximum around pH 6.0. It is increased in the presence of acetate ions but was not affected by citrate and phosphate ions.
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