ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2012
Exhaled breath condensate pH in patients with cystic fibrosis.
Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Exhaled Breath Analysis for Lung Cancer Detection: From VOCs Signatures to EBC-Based Liquid Biopsy and Clinical Translation.Thoracic cancer · 2026Review
- Article
- Comparative proteomic analysis of exhaled breath condensate between lung adenocarcinoma and CT-detected benign pulmonary nodule patients.Cancer biomarkers : section A of Disease markers · 2022Article
- Elimination of bacterial DNA during RNA isolation from sputum: Bashing bead vortexing is preferable over prolonged DNase treatment.PloS one · 2019Article
- Variability of breath condensate pH may contribute to the better understanding of non-allergic seasonal respiratory diseases.International journal of biometeorology · 2017Article
- Article
- Exhaled Breath Condensate: Technical and Diagnostic Aspects.TheScientificWorldJournal · 2015Review
- Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2014Article
- Predicting sputum eosinophilia in exacerbations of COPD using exhaled nitric oxide.Inflammation · 2013Article
- Exhaled breath condensate--from an analytical point of view.Biochemia medica · 2013Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
OBJECTIVE AND
designExhaled breath condensate (EBC) pH has been proposed as a useful, non-invasive marker of airway inflammation in pulmonary diseases. In this study we tested whether cystic fibrosis (CF) is associated with acidification of EBC, when pH is assessed by the CO(2) gas standardization method.
methodsEBC was collected using two different devices (EcoScreen and R-Tube) in 46 stable CF patients during routine clinical visits and in 28 healthy controls.
resultsMean EBC pH in CF patients and in healthy controls was similar (EcoScreen: CF patients: 6.38 ± 0.03 versus controls: 6.39 ± 0.03, p = 0.699; R-tube: CF patients: 5.94 ± 0.04 versus controls: 6.02 ± 0.03, p = 0.159). Inflammatory cell counts in spontaneously expectorated sputum obtained in a subset of patients (n = 20) showed no correlation with pH values. EBC samples collected with the R-tube were more acidic than those collected with the EcoScreen device (p < 0.001).
conclusionsOur data suggest that EBC pH does not discriminate between healthy controls and those with CF disease indicating that the clinical applicability of EBC pH measurements for assessing airway inflammation in CF is limited.
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